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Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study.
Solomon JJ, Danoff SK, Woodhead FA, Hurwitz S, Maurer R, Glaspole I, Dellaripa PF, Gooptu B, Vassallo R, Cox PG, Flaherty KR, Adamali HI, Gibbons MA, Troy L, Forrest IA, Lasky JA, Spencer LG, Golden J, Scholand MB, Chaudhuri N, Perrella MA, Lynch DA, Chambers DC, Kolb M, Spino C, Raghu G, Goldberg HJ, Rosas IO; TRAIL1 Network Investigators. Solomon JJ, et al. Among authors: hurwitz s. Lancet Respir Med. 2023 Jan;11(1):87-96. doi: 10.1016/S2213-2600(22)00260-0. Epub 2022 Sep 5. Lancet Respir Med. 2023. PMID: 36075242 Clinical Trial.
The Design and Rationale of the Trail1 Trial: A Randomized Double-Blind Phase 2 Clinical Trial of Pirfenidone in Rheumatoid Arthritis-Associated Interstitial Lung Disease.
Solomon JJ, Danoff SK, Goldberg HJ, Woodhead F, Kolb M, Chambers DC, DiFranco D, Spino C, Haynes-Harp S, Hurwitz S, Peters EB, Dellaripa PF, Rosas IO; Trail Network. Solomon JJ, et al. Among authors: hurwitz s. Adv Ther. 2019 Nov;36(11):3279-3287. doi: 10.1007/s12325-019-01086-2. Epub 2019 Sep 12. Adv Ther. 2019. PMID: 31515704 Clinical Trial.
A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS.
Fredenburgh LE, Perrella MA, Barragan-Bradford D, Hess DR, Peters E, Welty-Wolf KE, Kraft BD, Harris RS, Maurer R, Nakahira K, Oromendia C, Davies JD, Higuera A, Schiffer KT, Englert JA, Dieffenbach PB, Berlin DA, Lagambina S, Bouthot M, Sullivan AI, Nuccio PF, Kone MT, Malik MJ, Porras MAP, Finkelsztein E, Winkler T, Hurwitz S, Serhan CN, Piantadosi CA, Baron RM, Thompson BT, Choi AM. Fredenburgh LE, et al. Among authors: hurwitz s. JCI Insight. 2018 Dec 6;3(23):e124039. doi: 10.1172/jci.insight.124039. JCI Insight. 2018. PMID: 30518685 Free PMC article. Clinical Trial.
Zinc deficiency primes the lung for ventilator-induced injury.
Boudreault F, Pinilla-Vera M, Englert JA, Kho AT, Isabelle C, Arciniegas AJ, Barragan-Bradford D, Quintana C, Amador-Munoz D, Guan J, Choi KM; MICU Registry; Sholl L, Hurwitz S, Tschumperlin DJ, Baron RM. Boudreault F, et al. Among authors: hurwitz s. JCI Insight. 2017 Jun 2;2(11):e86507. doi: 10.1172/jci.insight.86507. eCollection 2017 Jun 2. JCI Insight. 2017. PMID: 28570269 Free PMC article.
716 results