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Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Neuron. 2022 Oct 5;110(19):3154-3167.e7. doi: 10.1016/j.neuron.2022.08.006. Epub 2022 Sep 9.
Neuron. 2022.
PMID: 36087581
Free PMC article.
Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Harris JA, Faust B, Gondin AB, Dämgen MA, Suomivuori CM, Veldhuis NA, Cheng Y, Dror RO, Thal DM, Manglik A.
Harris JA, et al. Among authors: damgen ma.
Nat Chem Biol. 2022 Jan;18(1):109-115. doi: 10.1038/s41589-021-00890-8. Epub 2021 Oct 28.
Nat Chem Biol. 2022.
PMID: 34711980
Free PMC article.
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State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane.
Dämgen MA, Biggin PC.
Dämgen MA, et al.
PLoS Comput Biol. 2021 Feb 11;17(2):e1007856. doi: 10.1371/journal.pcbi.1007856. eCollection 2021 Feb.
PLoS Comput Biol. 2021.
PMID: 33571182
Free PMC article.
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Computational methods to examine conformational changes and ligand-binding properties: Examples in neurobiology.
Dämgen MA, Biggin PC.
Dämgen MA, et al.
Neurosci Lett. 2019 May 1;700:9-16. doi: 10.1016/j.neulet.2018.03.004. Epub 2018 Mar 5.
Neurosci Lett. 2019.
PMID: 29518541
Review.
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A Refined Open State of the Glycine Receptor Obtained via Molecular Dynamics Simulations.
Dämgen MA, Biggin PC.
Dämgen MA, et al.
Structure. 2020 Jan 7;28(1):130-139.e2. doi: 10.1016/j.str.2019.10.019. Epub 2019 Nov 18.
Structure. 2020.
PMID: 31753620
Free PMC article.
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Comment on "On the Functional Annotation of Open-Channel Structures in the Glycine Receptor".
Dämgen MA, Zaki AM, Biggin PC.
Dämgen MA, et al.
Structure. 2020 Jun 2;28(6):601-603. doi: 10.1016/j.str.2020.04.021.
Structure. 2020.
PMID: 32492412
Free article.
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The Startle Disease Mutation E103K Impairs Activation of Human Homomeric α1 Glycine Receptors by Disrupting an Intersubunit Salt Bridge across the Agonist Binding Site.
Safar F, Hurdiss E, Erotocritou M, Greiner T, Lape R, Irvine MW, Fang G, Jane D, Yu R, Dämgen MA, Biggin PC, Sivilotti LG.
Safar F, et al. Among authors: damgen ma.
J Biol Chem. 2017 Mar 24;292(12):5031-5042. doi: 10.1074/jbc.M116.767616. Epub 2017 Feb 7.
J Biol Chem. 2017.
PMID: 28174298
Free PMC article.
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