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Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses.
Monticone G, Huang Z, Csibi F, Leit S, Ciccone D, Champhekar AS, Austin JE, Ucar DA, Hossain F, Ibba SV, Boulares AH, Carpino N, Xu K, Majumder S, Osborne BA, Loh C, Miele L. Monticone G, et al. Among authors: ucar da. Front Immunol. 2022 Aug 26;13:987298. doi: 10.3389/fimmu.2022.987298. eCollection 2022. Front Immunol. 2022. PMID: 36090975 Free PMC article.
Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses.
Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Hossain F, et al. Among authors: ucar da. Front Immunol. 2018 Jun 4;9:1288. doi: 10.3389/fimmu.2018.01288. eCollection 2018. Front Immunol. 2018. PMID: 29915603 Free PMC article. Review.
Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways.
Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, Burow M, Collins-Burow B, Pannuti A, Minter LM, Golde TE, Osborne BA, Miele L. Hossain F, et al. Among authors: ucar da. Front Oncol. 2018 Dec 4;8:575. doi: 10.3389/fonc.2018.00575. eCollection 2018. Front Oncol. 2018. PMID: 30564555 Free PMC article.
ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer.
Hoang VT, Matossian MD, Ucar DA, Elliott S, La J, Wright MK, Burks HE, Perles A, Hossain F, King CT, Browning VE, Bursavich J, Fang F, Del Valle L, Bhatt AB, Cavanaugh JE, Flaherty PT, Anbalagan M, Rowan BG, Bratton MR, Nephew KP, Miele L, Collins-Burow BM, Martin EC, Burow ME. Hoang VT, et al. Among authors: ucar da. Front Oncol. 2020 Aug 3;10:1164. doi: 10.3389/fonc.2020.01164. eCollection 2020. Front Oncol. 2020. PMID: 32850332 Free PMC article.
Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor.
Chang TC, Matossian MD, Elliott S, Burks HE, Sabol RA, Ucar DA, Wathieu H, Zabaleta J, Del Valle L, Gill S, Martin E, Riker AI, Miele L, Bunnell BA, Burow ME, Collins-Burow BM. Chang TC, et al. Among authors: ucar da. PLoS One. 2020 Oct 9;15(10):e0226464. doi: 10.1371/journal.pone.0226464. eCollection 2020. PLoS One. 2020. PMID: 33035223 Free PMC article.
Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer.
Hossain F, Ucar DA, Monticone G, Ran Y, Majumder S, Larter K, Luu H, Wyczechowska D, Heidari S, Xu K, Shanthalingam S, Matossian M, Xi Y, Burow M, Collins-Burow B, Del Valle L, Hicks C, Zabaleta J, Golde T, Osborne B, Miele L. Hossain F, et al. Among authors: ucar da. Front Immunol. 2023 Oct 13;14:1244159. doi: 10.3389/fimmu.2023.1244159. eCollection 2023. Front Immunol. 2023. PMID: 37901240 Free PMC article.
A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways.
Matossian MD, Burks HE, Elliott S, Hoang VT, Zuercher WJ, Wells C, Drewry DH, Kapadia N, Chang T, Yan T, Windsor GO, Nguyen K, Fang F, Nephew KP, Buechlein A, Rusch DB, Sabol RA, Ucar DA, Zabaleta J, Miele L, Bunnell BA, Collins-Burow BM, Burow ME. Matossian MD, et al. Among authors: ucar da. Anticancer Drugs. 2020 Sep;31(8):759-775. doi: 10.1097/CAD.0000000000000962. Anticancer Drugs. 2020. PMID: 32796402 Free PMC article.
Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation.
Hoang VT, Matossian MD, La J, Hoang K, Ucar DA, Elliott S, Burks HE, Wright TD, Patel S, Bhatt A, Phamduy T, Chrisey D, Buechlein A, Rusch DB, Nephew KP, Anbalagan M, Rowan B, Cavanaugh JE, Flaherty PT, Miele L, Collins-Burow BM, Burow ME. Hoang VT, et al. Among authors: ucar da. J Cell Biochem. 2021 Aug;122(8):835-850. doi: 10.1002/jcb.29916. Epub 2021 Apr 20. J Cell Biochem. 2021. PMID: 33876843
25 results