Lettice LA - Search Results

1

Cohesin is required for long-range enhancer action at the Shh locus.

Kane L, Williamson I, Flyamer IM, Kumar Y, Hill RE, Lettice LA, Bickmore WA. Kane L, et al. Among authors: lettice la. Nat Struct Mol Biol. 2022 Sep;29(9):891-897. doi: 10.1038/s41594-022-00821-8. Epub 2022 Sep 12. Nat Struct Mol Biol. 2022. PMID: 36097291 Free PMC article.

2

Alterations to the remote control of Shh gene expression cause congenital abnormalities.

Hill RE, Lettice LA. Hill RE, et al. Among authors: lettice la. Philos Trans R Soc Lond B Biol Sci. 2013 May 6;368(1620):20120357. doi: 10.1098/rstb.2012.0357. Print 2013. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 23650631 Free PMC article.

3

Mapping the Shh long-range regulatory domain.

Anderson E, Devenney PS, Hill RE, Lettice LA. Anderson E, et al. Among authors: lettice la. Development. 2014 Oct;141(20):3934-43. doi: 10.1242/dev.108480. Epub 2014 Sep 24. Development. 2014. PMID: 25252942 Free PMC article.

4

Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity.

Williamson I, Lettice LA, Hill RE, Bickmore WA. Williamson I, et al. Among authors: lettice la. Development. 2016 Aug 15;143(16):2994-3001. doi: 10.1242/dev.139188. Epub 2016 Jul 11. Development. 2016. PMID: 27402708 Free PMC article.

5

SBE6: a novel long-range enhancer involved in driving sonic hedgehog expression in neural progenitor cells.

Benabdallah NS, Gautier P, Hekimoglu-Balkan B, Lettice LA, Bhatia S, Bickmore WA. Benabdallah NS, et al. Among authors: lettice la. Open Biol. 2016 Nov;6(11):160197. doi: 10.1098/rsob.160197. Open Biol. 2016. PMID: 27852806 Free PMC article.

6

Developmentally regulated Shh expression is robust to TAD perturbations.

Williamson I, Kane L, Devenney PS, Flyamer IM, Anderson E, Kilanowski F, Hill RE, Bickmore WA, Lettice LA. Williamson I, et al. Among authors: lettice la. Development. 2019 Sep 30;146(19):dev179523. doi: 10.1242/dev.179523. Development. 2019. PMID: 31511252 Free PMC article.

7

A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly.

Lettice LA, Heaney SJ, Purdie LA, Li L, de Beer P, Oostra BA, Goode D, Elgar G, Hill RE, de Graaff E. Lettice LA, et al. Hum Mol Genet. 2003 Jul 15;12(14):1725-35. doi: 10.1093/hmg/ddg180. Hum Mol Genet. 2003. PMID: 12837695

8

Preaxial polydactyly: a model for defective long-range regulation in congenital abnormalities.

Lettice LA, Hill RE. Lettice LA, et al. Curr Opin Genet Dev. 2005 Jun;15(3):294-300. doi: 10.1016/j.gde.2005.04.002. Curr Opin Genet Dev. 2005. PMID: 15917205 Review.

9

Enhancer-adoption as a mechanism of human developmental disease.

Lettice LA, Daniels S, Sweeney E, Venkataraman S, Devenney PS, Gautier P, Morrison H, Fantes J, Hill RE, FitzPatrick DR. Lettice LA, et al. Hum Mutat. 2011 Dec;32(12):1492-9. doi: 10.1002/humu.21615. Epub 2011 Oct 20. Hum Mutat. 2011. PMID: 21948517

10

Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly.

Lettice LA, Williamson I, Wiltshire JH, Peluso S, Devenney PS, Hill AE, Essafi A, Hagman J, Mort R, Grimes G, DeAngelis CL, Hill RE. Lettice LA, et al. Dev Cell. 2012 Feb 14;22(2):459-67. doi: 10.1016/j.devcel.2011.12.010. Dev Cell. 2012. PMID: 22340503 Free PMC article.

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