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Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine.
Nat Chem Biol. 2022 Dec;18(12):1388-1398. doi: 10.1038/s41589-022-01098-0. Epub 2022 Sep 12.
Nat Chem Biol. 2022.
PMID: 36097295
Free PMC article.
Author Correction: Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine.
Kavanagh ME, Horning BD, Khattri R, Roy N, Lu JP, Whitby LR, Ye E, Brannon JC, Parker A, Chick JM, Eissler CL, Wong AJ, Rodriguez JL, Rodiles S, Masuda K, Teijaro JR, Simon GM, Patricelli MP, Cravatt BF.
Kavanagh ME, et al. Among authors: horning bd.
Nat Chem Biol. 2022 Nov;18(11):1288. doi: 10.1038/s41589-022-01181-6.
Nat Chem Biol. 2022.
PMID: 36180594
No abstract available.
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Proteome-wide covalent ligand discovery in native biological systems.
Backus KM, Correia BE, Lum KM, Forli S, Horning BD, González-Páez GE, Chatterjee S, Lanning BR, Teijaro JR, Olson AJ, Wolan DW, Cravatt BF.
Backus KM, et al. Among authors: horning bd.
Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
Nature. 2016.
PMID: 27309814
Free PMC article.
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Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ.
Lee HY, Suciu RM, Horning BD, Vinogradova EV, Ulanovskaya OA, Cravatt BF.
Lee HY, et al. Among authors: horning bd.
Bioorg Med Chem Lett. 2018 Sep 1;28(16):2682-2687. doi: 10.1016/j.bmcl.2018.04.017. Epub 2018 Apr 10.
Bioorg Med Chem Lett. 2018.
PMID: 29731364
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Chemical Proteomic Profiling of Human Methyltransferases.
Horning BD, Suciu RM, Ghadiri DA, Ulanovskaya OA, Matthews ML, Lum KM, Backus KM, Brown SJ, Rosen H, Cravatt BF.
Horning BD, et al.
J Am Chem Soc. 2016 Oct 12;138(40):13335-13343. doi: 10.1021/jacs.6b07830. Epub 2016 Sep 30.
J Am Chem Soc. 2016.
PMID: 27689866
Free PMC article.
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Chemoproteomic profiling and discovery of protein electrophiles in human cells.
Matthews ML, He L, Horning BD, Olson EJ, Correia BE, Yates JR 3rd, Dawson PE, Cravatt BF.
Matthews ML, et al. Among authors: horning bd.
Nat Chem. 2017 Mar;9(3):234-243. doi: 10.1038/nchem.2645. Epub 2016 Oct 31.
Nat Chem. 2017.
PMID: 28221344
Free PMC article.
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Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer.
Bar-Peled L, Kemper EK, Suciu RM, Vinogradova EV, Backus KM, Horning BD, Paul TA, Ichu TA, Svensson RU, Olucha J, Chang MW, Kok BP, Zhu Z, Ihle NT, Dix MM, Jiang P, Hayward MM, Saez E, Shaw RJ, Cravatt BF.
Bar-Peled L, et al. Among authors: horning bd.
Cell. 2017 Oct 19;171(3):696-709.e23. doi: 10.1016/j.cell.2017.08.051. Epub 2017 Sep 28.
Cell. 2017.
PMID: 28965760
Free PMC article.
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Nine-step enantioselective total synthesis of (-)-vincorine.
Horning BD, MacMillan DW.
Horning BD, et al.
J Am Chem Soc. 2013 May 1;135(17):6442-5. doi: 10.1021/ja402933s. Epub 2013 Apr 19.
J Am Chem Soc. 2013.
PMID: 23586842
Free PMC article.
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