Patricelli MP - Search Results

1

Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine.

Kavanagh ME, Horning BD, Khattri R, Roy N, Lu JP, Whitby LR, Ye E, Brannon JC, Parker A, Chick JM, Eissler CL, Wong AJ, Rodriguez JL, Rodiles S, Masuda K, Teijaro JR, Simon GM, Patricelli MP, Cravatt BF. Kavanagh ME, et al. Among authors: patricelli mp. Nat Chem Biol. 2022 Dec;18(12):1388-1398. doi: 10.1038/s41589-022-01098-0. Epub 2022 Sep 12. Nat Chem Biol. 2022. PMID: 36097295 Free PMC article.

2

Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: identification of the transmembrane domain as a site for oligomerization.

Patricelli MP, Lashuel HA, Giang DK, Kelly JW, Cravatt BF. Patricelli MP, et al. Biochemistry. 1998 Oct 27;37(43):15177-87. doi: 10.1021/bi981733n. Biochemistry. 1998. PMID: 9790682

3

An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase.

Patricelli MP, Patterson JE, Boger DL, Cravatt BF. Patricelli MP, et al. Bioorg Med Chem Lett. 1998 Mar 17;8(6):613-8. doi: 10.1016/s0960-894x(98)00073-0. Bioorg Med Chem Lett. 1998. PMID: 9871570

4

Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: a probe of structural and conformational features contributing to inhibition.

Boger DL, Sato H, Lerner AE, Austin BJ, Patterson JE, Patricelli MP, Cravatt BF. Boger DL, et al. Among authors: patricelli mp. Bioorg Med Chem Lett. 1999 Jan 18;9(2):265-70. doi: 10.1016/s0960-894x(98)00734-3. Bioorg Med Chem Lett. 1999. PMID: 10021942

5

Chemical and mutagenic investigations of fatty acid amide hydrolase: evidence for a family of serine hydrolases with distinct catalytic properties.

Patricelli MP, Lovato MA, Cravatt BF. Patricelli MP, et al. Biochemistry. 1999 Aug 3;38(31):9804-12. doi: 10.1021/bi990637z. Biochemistry. 1999. PMID: 10433686

6

Fatty acid amide hydrolase competitively degrades bioactive amides and esters through a nonconventional catalytic mechanism.

Patricelli MP, Cravatt BF. Patricelli MP, et al. Biochemistry. 1999 Oct 26;38(43):14125-30. doi: 10.1021/bi991876p. Biochemistry. 1999. PMID: 10571985

7

Activity-based protein profiling: the serine hydrolases.

Liu Y, Patricelli MP, Cravatt BF. Liu Y, et al. Among authors: patricelli mp. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14694-9. doi: 10.1073/pnas.96.26.14694. Proc Natl Acad Sci U S A. 1999. PMID: 10611275 Free PMC article.

8

Clarifying the catalytic roles of conserved residues in the amidase signature family.

Patricelli MP, Cravatt BF. Patricelli MP, et al. J Biol Chem. 2000 Jun 23;275(25):19177-84. doi: 10.1074/jbc.M001607200. J Biol Chem. 2000. PMID: 10764768 Free article.

9

Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide.

Boger DL, Sato H, Lerner AE, Hedrick MP, Fecik RA, Miyauchi H, Wilkie GD, Austin BJ, Patricelli MP, Cravatt BF. Boger DL, et al. Among authors: patricelli mp. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5044-9. doi: 10.1073/pnas.97.10.5044. Proc Natl Acad Sci U S A. 2000. PMID: 10805767 Free PMC article.

10

Fatty acid amide hydrolase substrate specificity.

Boger DL, Fecik RA, Patterson JE, Miyauchi H, Patricelli MP, Cravatt BF. Boger DL, et al. Among authors: patricelli mp. Bioorg Med Chem Lett. 2000 Dec 4;10(23):2613-6. doi: 10.1016/s0960-894x(00)00528-x. Bioorg Med Chem Lett. 2000. PMID: 11128635

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