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Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants.
Prakash R, Rawal Y, Sullivan MR, Grundy MK, Bret H, Mihalevic MJ, Rein HL, Baird JM, Darrah K, Zhang F, Wang R, Traina TA, Radke MR, Kaufmann SH, Swisher EM, Guérois R, Modesti M, Sung P, Jasin M, Bernstein KA. Prakash R, et al. Among authors: wang r. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2202727119. doi: 10.1073/pnas.2202727119. Epub 2022 Sep 13. Proc Natl Acad Sci U S A. 2022. PMID: 36099300 Free PMC article.
Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex.
Prakash R, Sandoval T, Morati F, Zagelbaum JA, Lim PX, White T, Taylor B, Wang R, Desclos ECB, Sullivan MR, Rein HL, Bernstein KA, Krawczyk PM, Gautier J, Modesti M, Vanoli F, Jasin M. Prakash R, et al. Among authors: wang r. Nat Commun. 2021 Jul 12;12(1):4255. doi: 10.1038/s41467-021-24205-6. Nat Commun. 2021. PMID: 34253720 Free PMC article.
XRCC3 loss leads to midgestational embryonic lethality in mice.
Prakash R, Freyer L, Saiz N, Gavrilov S, Wang RQ, Romanienko PJ, Lacy E, Hadjantonakis AK, Jasin M. Prakash R, et al. Among authors: wang rq. DNA Repair (Amst). 2021 Dec;108:103227. doi: 10.1016/j.dnarep.2021.103227. Epub 2021 Sep 22. DNA Repair (Amst). 2021. PMID: 34601382 Free PMC article.
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