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Nanobodies identify an activated state of the TRIB2 pseudokinase.
Structure. 2022 Nov 3;30(11):1518-1529.e5. doi: 10.1016/j.str.2022.08.006. Epub 2022 Sep 14.
Structure. 2022.
PMID: 36108635
Free article.
Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1.
Jamieson SA, Ruan Z, Burgess AE, Curry JR, McMillan HD, Brewster JL, Dunbier AK, Axtman AD, Kannan N, Mace PD.
Jamieson SA, et al. Among authors: mcmillan hd.
Sci Signal. 2018 Sep 25;11(549):eaau0597. doi: 10.1126/scisignal.aau0597.
Sci Signal. 2018.
PMID: 30254053
Free PMC article.
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Structure vs. Function of TRIB1-Myeloid Neoplasms and Beyond.
McMillan HD, Keeshan K, Dunbier AK, Mace PD.
McMillan HD, et al.
Cancers (Basel). 2021 Jun 19;13(12):3060. doi: 10.3390/cancers13123060.
Cancers (Basel). 2021.
PMID: 34205360
Free PMC article.
Review.
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Structural and biophysical characterization of Tribbles homolog 1.
Jamieson SA, McMillan HD, Mace PD.
Jamieson SA, et al. Among authors: mcmillan hd.
Methods Enzymol. 2022;667:37-58. doi: 10.1016/bs.mie.2022.03.023. Epub 2022 Apr 8.
Methods Enzymol. 2022.
PMID: 35525548
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