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Structures of α-synuclein filaments from human brains with Lewy pathology.
Yang Y, Shi Y, Schweighauser M, Zhang X, Kotecha A, Murzin AG, Garringer HJ, Cullinane PW, Saito Y, Foroud T, Warner TT, Hasegawa K, Vidal R, Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SHW, Goedert M. Yang Y, et al. Among authors: hasegawa k, hasegawa m. Nature. 2022 Oct;610(7933):791-795. doi: 10.1038/s41586-022-05319-3. Epub 2022 Sep 15. Nature. 2022. PMID: 36108674 Free PMC article.
Variants associated with Gaucher disease in multiple system atrophy.
Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Takashima H, Kikuchi A, Aoki M, Ishiura H, Yasuda T, Date H, Ahsan B, Iwata A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S. Mitsui J, et al. Among authors: hasegawa k. Ann Clin Transl Neurol. 2015 Apr;2(4):417-26. doi: 10.1002/acn3.185. Epub 2015 Feb 28. Ann Clin Transl Neurol. 2015. PMID: 25909086 Free PMC article.
Structures of α-synuclein filaments from multiple system atrophy.
Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M. Schweighauser M, et al. Among authors: hasegawa k, hasegawa m. Nature. 2020 Sep;585(7825):464-469. doi: 10.1038/s41586-020-2317-6. Epub 2020 May 27. Nature. 2020. PMID: 32461689 Free PMC article.
Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy.
Lövestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW. Lövestam S, et al. Among authors: hasegawa k, hasegawa m. FEBS Open Bio. 2021 Apr;11(4):999-1013. doi: 10.1002/2211-5463.13110. Epub 2021 Feb 24. FEBS Open Bio. 2021. PMID: 33548114 Free PMC article.
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lövestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, Lashley T, Revesz T, Kovacs GG, van Swieten J, Takao M, Hasegawa M, Ghetti B, Spillantini MG, Ryskeldi-Falcon B, Murzin AG, Goedert M, Scheres SHW. Schweighauser M, et al. Among authors: hasegawa k, hasegawa m. Nature. 2022 May;605(7909):310-314. doi: 10.1038/s41586-022-04650-z. Epub 2022 Mar 28. Nature. 2022. PMID: 35344985 Free PMC article.
Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43.
Tarutani A, Adachi T, Akatsu H, Hashizume Y, Hasegawa K, Saito Y, Robinson AC, Mann DMA, Yoshida M, Murayama S, Hasegawa M. Tarutani A, et al. Among authors: hasegawa k, hasegawa m. Acta Neuropathol. 2022 Jun;143(6):613-640. doi: 10.1007/s00401-022-02426-3. Epub 2022 May 5. Acta Neuropathol. 2022. PMID: 35513543 Free PMC article. Review.
Neuropathology of spinocerebellar ataxia type 8: Common features and unique tauopathy.
Yonenobu Y, Beck G, Kido K, Maeda N, Yamashita R, Inoue K, Saito Y, Hasegawa M, Ito H, Hasegawa K, Morii E, Iwaki T, Murayama S, Mochizuki H. Yonenobu Y, et al. Among authors: hasegawa k, hasegawa m. Neuropathology. 2023 Oct;43(5):351-361. doi: 10.1111/neup.12894. Epub 2023 Jan 26. Neuropathology. 2023. PMID: 36703300
4,340 results