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Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling.
Mishra S, Cosentino C, Tamta AK, Khan D, Srinivasan S, Ravi V, Abbotto E, Arathi BP, Kumar S, Jain A, Ramaian AS, Kizkekra SM, Rajagopal R, Rao S, Krishna S, Asirvatham-Jeyaraj N, Haggerty ER, Silberman DM, Kurland IJ, Veeranna RP, Jayavelu T, Bruzzone S, Mostoslavsky R, Sundaresan NR. Mishra S, et al. Among authors: asirvatham jeyaraj n. Nat Commun. 2022 Sep 15;13(1):5415. doi: 10.1038/s41467-022-32905-w. Nat Commun. 2022. PMID: 36109503 Free PMC article.
SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARγ.
Khan D, Ara T, Ravi V, Rajagopal R, Tandon H, Parvathy J, Gonzalez EA, Asirvatham-Jeyaraj N, Krishna S, Mishra S, Raghu S, Bhati AS, Tamta AK, Dasgupta S, Kolthur-Seetharam U, Etchegaray JP, Mostoslavsky R, Rao PSM, Srinivasan N, Sundaresan NR. Khan D, et al. Among authors: asirvatham jeyaraj n. Cell Rep. 2021 Jun 1;35(9):109190. doi: 10.1016/j.celrep.2021.109190. Cell Rep. 2021. PMID: 34077730 Free PMC article.
Obesity-induced sympathoexcitation is associated with Nrf2 dysfunction in the rostral ventrolateral medulla.
Balasubramanian P, Asirvatham-Jeyaraj N, Monteiro R, Sivasubramanian MK, Hall D, Subramanian M. Balasubramanian P, et al. Among authors: asirvatham jeyaraj n. Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R435-R444. doi: 10.1152/ajpregu.00206.2019. Epub 2019 Dec 11. Am J Physiol Regul Integr Comp Physiol. 2020. PMID: 31823672 Free PMC article.
Targeted afferent renal denervation reduces arterial pressure but not renal inflammation in established DOCA-salt hypertension in the rat.
Banek CT, Gauthier MM, Baumann DC, Van Helden D, Asirvatham-Jeyaraj N, Panoskaltsis-Mortari A, Fink GD, Osborn JW. Banek CT, et al. Among authors: asirvatham jeyaraj n. Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R883-R891. doi: 10.1152/ajpregu.00416.2017. Epub 2018 Mar 7. Am J Physiol Regul Integr Comp Physiol. 2018. PMID: 29513561 Free PMC article.
Resting Afferent Renal Nerve Discharge and Renal Inflammation: Elucidating the Role of Afferent and Efferent Renal Nerves in Deoxycorticosterone Acetate Salt Hypertension.
Banek CT, Knuepfer MM, Foss JD, Fiege JK, Asirvatham-Jeyaraj N, Van Helden D, Shimizu Y, Osborn JW. Banek CT, et al. Among authors: asirvatham jeyaraj n. Hypertension. 2016 Dec;68(6):1415-1423. doi: 10.1161/HYPERTENSIONAHA.116.07850. Epub 2016 Oct 3. Hypertension. 2016. PMID: 27698066 Free PMC article.
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