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Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signaling.
Mishra S, Cosentino C, Tamta AK, Khan D, Srinivasan S, Ravi V, Abbotto E, Arathi BP, Kumar S, Jain A, Ramaian AS, Kizkekra SM, Rajagopal R, Rao S, Krishna S, Asirvatham-Jeyaraj N, Haggerty ER, Silberman DM, Kurland IJ, Veeranna RP, Jayavelu T, Bruzzone S, Mostoslavsky R, Sundaresan NR. Mishra S, et al. Among authors: rajagopal r. Nat Commun. 2022 Sep 15;13(1):5415. doi: 10.1038/s41467-022-32905-w. Nat Commun. 2022. PMID: 36109503 Free PMC article.
SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARγ.
Khan D, Ara T, Ravi V, Rajagopal R, Tandon H, Parvathy J, Gonzalez EA, Asirvatham-Jeyaraj N, Krishna S, Mishra S, Raghu S, Bhati AS, Tamta AK, Dasgupta S, Kolthur-Seetharam U, Etchegaray JP, Mostoslavsky R, Rao PSM, Srinivasan N, Sundaresan NR. Khan D, et al. Among authors: rajagopal r. Cell Rep. 2021 Jun 1;35(9):109190. doi: 10.1016/j.celrep.2021.109190. Cell Rep. 2021. PMID: 34077730 Free PMC article.
Impact of a varied set of stimuli on a suite of immunological parameters within peripheral blood mononuclear cells: toward a non-animal approach for assessing immune modulation by materials intended for human use.
Cochrane S, Rajagopal R, Sheffield D, Stewart F, Hathaway L, Barnes NM, Qureshi O, Gordon J. Cochrane S, et al. Among authors: rajagopal r. Front Toxicol. 2024 Apr 26;6:1335110. doi: 10.3389/ftox.2024.1335110. eCollection 2024. Front Toxicol. 2024. PMID: 38737195 Free PMC article.
500 results