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Effects of a Novel Beta Lactam Compound, MC-100093, on the Expression of Glutamate Transporters/Receptors and Ethanol Drinking Behavior of Alcohol-Preferring Rats.
J Pharmacol Exp Ther. 2022 Dec;383(3):208-216. doi: 10.1124/jpet.122.001147. Epub 2022 Sep 24.
J Pharmacol Exp Ther. 2022.
PMID: 36153003
Free PMC article.
Novel compounds that reverse the disease phenotype in Type 2 Gaucher disease patient-derived cells.
Childers W, Fan R, Martinez R, Colussi DJ, Melenski E, Liu Y, Gordon J, Abou-Gharbia M, Jacobson MA.
Childers W, et al. Among authors: melenski e.
Bioorg Med Chem Lett. 2020 Jan 15;30(2):126806. doi: 10.1016/j.bmcl.2019.126806. Epub 2019 Nov 11.
Bioorg Med Chem Lett. 2020.
PMID: 31757667
Free PMC article.
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Novel progesterone receptor modulators: 4-aryl-phenylsulfonamides.
McComas C, Cohen J, Huselton C, Marella M, Melenski E, Mugford C, Slayden O, Winneker R, Wrobel J, Yudt MR, Fensome A.
McComas C, et al. Among authors: melenski e.
Bioorg Med Chem Lett. 2012 Dec 1;22(23):7119-22. doi: 10.1016/j.bmcl.2012.09.077. Epub 2012 Sep 29.
Bioorg Med Chem Lett. 2012.
PMID: 23079530
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Design, synthesis, and SAR of new pyrrole-oxindole progesterone receptor modulators leading to 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348).
Fensome A, Adams WR, Adams AL, Berrodin TJ, Cohen J, Huselton C, Illenberger A, Kern JC, Hudak VA, Marella MA, Melenski EG, McComas CC, Mugford CA, Slayden OD, Yudt M, Zhang Z, Zhang P, Zhu Y, Winneker RC, Wrobel JE.
Fensome A, et al. Among authors: melenski eg.
J Med Chem. 2008 Mar 27;51(6):1861-73. doi: 10.1021/jm701080t. Epub 2008 Mar 5.
J Med Chem. 2008.
PMID: 18318463
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