Chen K - Search Results

1

SECANT: a biology-guided semi-supervised method for clustering, classification, and annotation of single-cell multi-omics.

Wang X, Xu Z, Hu H, Zhou X, Zhang Y, Lafyatis R, Chen K, Huang H, Ding Y, Duerr RH, Chen W. Wang X, et al. Among authors: chen k, chen w. PNAS Nexus. 2022 Aug 19;1(4):pgac165. doi: 10.1093/pnasnexus/pgac165. eCollection 2022 Sep. PNAS Nexus. 2022. PMID: 36157595 Free PMC article.

2

AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality.

Zhang H, Luo J, Alcorn JF, Chen K, Fan S, Pilewski J, Liu A, Chen W, Kolls JK, Wang J. Zhang H, et al. Among authors: chen k, chen w. J Immunol. 2017 Jun 1;198(11):4383-4393. doi: 10.4049/jimmunol.1600714. Epub 2017 Apr 19. J Immunol. 2017. PMID: 28424239 Free PMC article.

3

A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies.

Sun Z, Chen L, Xin H, Jiang Y, Huang Q, Cillo AR, Tabib T, Kolls JK, Bruno TC, Lafyatis R, Vignali DAA, Chen K, Ding Y, Hu M, Chen W. Sun Z, et al. Among authors: chen k, chen l, chen w. Nat Commun. 2019 Apr 9;10(1):1649. doi: 10.1038/s41467-019-09639-3. Nat Commun. 2019. PMID: 30967541 Free PMC article.

4

Transcriptomic Responses to Ivacaftor and Prediction of Ivacaftor Clinical Responsiveness.

Sun T, Sun Z, Jiang Y, Ferguson AA, Pilewski JM, Kolls JK, Chen W, Chen K. Sun T, et al. Among authors: chen k, chen w. Am J Respir Cell Mol Biol. 2019 Nov;61(5):643-652. doi: 10.1165/rcmb.2019-0032OC. Am J Respir Cell Mol Biol. 2019. PMID: 30995102 Free PMC article.

5

BREM-SC: a bayesian random effects mixture model for joint clustering single cell multi-omics data.

Wang X, Sun Z, Zhang Y, Xu Z, Xin H, Huang H, Duerr RH, Chen K, Ding Y, Chen W. Wang X, et al. Among authors: chen k, chen w. Nucleic Acids Res. 2020 Jun 19;48(11):5814-5824. doi: 10.1093/nar/gkaa314. Nucleic Acids Res. 2020. PMID: 32379315 Free PMC article.

6

Artificial-cell-type aware cell-type classification in CITE-seq.

Lian Q, Xin H, Ma J, Konnikova L, Chen W, Gu J, Chen K. Lian Q, et al. Among authors: chen k, chen w. Bioinformatics. 2020 Jul 1;36(Suppl_1):i542-i550. doi: 10.1093/bioinformatics/btaa467. Bioinformatics. 2020. PMID: 32657383 Free PMC article.

7

GMM-Demux: sample demultiplexing, multiplet detection, experiment planning, and novel cell-type verification in single cell sequencing.

Xin H, Lian Q, Jiang Y, Luo J, Wang X, Erb C, Xu Z, Zhang X, Heidrich-O'Hare E, Yan Q, Duerr RH, Chen K, Chen W. Xin H, et al. Among authors: chen k, chen w. Genome Biol. 2020 Jul 30;21(1):188. doi: 10.1186/s13059-020-02084-2. Genome Biol. 2020. PMID: 32731885 Free PMC article.

8

A road map from single-cell transcriptome to patient classification for the immune response to trauma.

Chen T, Delano MJ, Chen K, Sperry JL, Namas RA, Lamparello AJ, Deng M, Conroy J, Moldawer LL, Efron PA, Loughran P, Seymour C, Angus DC, Vodovotz Y, Chen W, Billiar TR. Chen T, et al. Among authors: chen k, chen w. JCI Insight. 2021 Jan 25;6(2):e145108. doi: 10.1172/jci.insight.145108. JCI Insight. 2021. PMID: 33320841 Free PMC article.

9

Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD.

Li X, Noell G, Tabib T, Gregory AD, Trejo Bittar HE, Vats R, Kaminski TW, Sembrat J, Snyder ME, Chandra D, Chen K, Zou C, Zhang Y, Sundd P, McDyer JF, Sciurba F, Rojas M, Lafyatis R, Shapiro SD, Faner R, Nyunoya T. Li X, et al. Among authors: chen k. Respir Res. 2021 Apr 6;22(1):100. doi: 10.1186/s12931-021-01675-2. Respir Res. 2021. PMID: 33823868 Free PMC article.

10

β-Agonist exposure preferentially impacts lung macrophage cyclic AMP-related gene expression in asthma and asthma COPD overlap syndrome.

Moghbeli K, Valenzi E, Naramore R, Sembrat JC, Chen K, Rojas MM, Wenzel SE, Lafyatis R, Modena B, Weathington NM. Moghbeli K, et al. Among authors: chen k. Am J Physiol Lung Cell Mol Physiol. 2021 Nov 1;321(5):L837-L843. doi: 10.1152/ajplung.00260.2021. Epub 2021 Sep 8. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34494468 Free PMC article.

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