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Page 1
Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody.
Quijada H, Bermudez T, Kempf CL, Valera DG, Garcia AN, Camp SM, Song JH, Franco E, Burt JK, Sun B, Mascarenhas JB, Burns K, Gaber A, Oita RC, Reyes Hernon V, Barber C, Moreno-Vinasco L, Sun X, Cress AE, Martin D, Liu Z, Desai AA, Natarajan V, Jacobson JR, Dudek SM, Bime C, Sammani S, Garcia JGN. Quijada H, et al. Among authors: kempf cl. Eur Respir J. 2021 May 6;57(5):2002536. doi: 10.1183/13993003.02536-2020. Print 2021 May. Eur Respir J. 2021. PMID: 33243842 Free PMC article.
Involvement of eNAMPT/TLR4 signaling in murine radiation pneumonitis: protection by eNAMPT neutralization.
Garcia AN, Casanova NG, Valera DG, Sun X, Song JH, Kempf CL, Moreno-Vinasco L, Burns K, Bermudez T, Valdez M, Cuellar G, Gregory T, Oita RC, Hernon VR, Barber C, Camp SM, Martin D, Liu Z, Bime C, Sammani S, Cress AE, Garcia JG. Garcia AN, et al. Among authors: kempf cl. Transl Res. 2022 Jan;239:44-57. doi: 10.1016/j.trsl.2021.06.002. Epub 2021 Jun 15. Transl Res. 2022. PMID: 34139379 Free PMC article.
eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling.
Bermudez T, Sammani S, Song JH, Hernon VR, Kempf CL, Garcia AN, Burt J, Hufford M, Camp SM, Cress AE, Desai AA, Natarajan V, Jacobson JR, Dudek SM, Cancio LC, Alvarez J, Rafikov R, Li Y, Zhang DD, Casanova NG, Bime C, Garcia JGN. Bermudez T, et al. Among authors: kempf cl. Sci Rep. 2022 Jan 13;12(1):696. doi: 10.1038/s41598-021-04444-9. Sci Rep. 2022. PMID: 35027578 Free PMC article.
eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis.
Garcia AN, Casanova NG, Kempf CL, Bermudez T, Valera DG, Song JH, Sun X, Cai H, Moreno-Vinasco L, Gregory T, Oita RC, Hernon VR, Camp SM, Rogers C, Kyubwa EM, Menon N, Axtelle J, Rappaport J, Bime C, Sammani S, Cress AE, Garcia JGN. Garcia AN, et al. Among authors: kempf cl. Am J Respir Cell Mol Biol. 2022 May;66(5):497-509. doi: 10.1165/rcmb.2021-0357OC. Am J Respir Cell Mol Biol. 2022. PMID: 35167418 Free PMC article.
eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury.
Sammani S, Bermudez T, Kempf CL, Song JH, Fleming JC, Reyes Hernon V, Hufford M, Tang L, Cai H, Camp SM, Natarajan V, Jacobson JR, Dudek SM, Martin DR, Karmonik C, Sun X, Sun B, Casanova NG, Bime C, Garcia JGN. Sammani S, et al. Among authors: kempf cl. Front Physiol. 2022 Jun 22;13:916159. doi: 10.3389/fphys.2022.916159. eCollection 2022. Front Physiol. 2022. PMID: 35812318 Free PMC article.
Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α.
Sun X, Sun BL, Babicheva A, Vanderpool R, Oita RC, Casanova N, Tang H, Gupta A, Lynn H, Gupta G, Rischard F, Sammani S, Kempf CL, Moreno-Vinasco L, Ahmed M, Camp SM, Wang J, Desai AA, Yuan JX, Garcia JGN. Sun X, et al. Among authors: kempf cl. Am J Respir Cell Mol Biol. 2020 Jul;63(1):92-103. doi: 10.1165/rcmb.2019-0164OC. Am J Respir Cell Mol Biol. 2020. PMID: 32142369 Free PMC article.
Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb.
Ahmed M, Zaghloul N, Zimmerman P, Casanova NG, Sun X, Song JH, Hernon VR, Sammani S, Rischard F, Rafikova O, Rafikov R, Makino A, Kempf CL, Camp SM, Wang J, Desai AA, Lussier Y, Yuan JX, Garcia JGN. Ahmed M, et al. Among authors: kempf cl. Pulm Circ. 2021 Nov 12;11(4):20458940211059712. doi: 10.1177/20458940211059712. eCollection 2021 Oct-Dec. Pulm Circ. 2021. PMID: 34790349 Free PMC article.
Genome-Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor.
Bime C, Pouladi N, Sammani S, Batai K, Casanova N, Zhou T, Kempf CL, Sun X, Camp SM, Wang T, Kittles RA, Lussier YA, Jones TK, Reilly JP, Meyer NJ, Christie JD, Karnes JH, Gonzalez-Garay M, Christiani DC, Yates CR, Wurfel MM, Meduri GU, Garcia JGN. Bime C, et al. Among authors: kempf cl. Am J Respir Crit Care Med. 2018 Jun 1;197(11):1421-1432. doi: 10.1164/rccm.201705-0961OC. Am J Respir Crit Care Med. 2018. PMID: 29425463 Free PMC article.
26 results