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S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair.
Amar-Schwartz A, Ben Hur V, Jbara A, Cohen Y, Barnabas GD, Arbib E, Siegfried Z, Mashahreh B, Hassouna F, Shilo A, Abu-Odeh M, Berger M, Wiener R, Aqeilan R, Geiger T, Karni R. Amar-Schwartz A, et al. Among authors: aqeilan r. Elife. 2022 Oct 3;11:e79128. doi: 10.7554/eLife.79128. Elife. 2022. PMID: 36189922 Free PMC article.
Wwox inactivation enhances mammary tumorigenesis.
Abdeen SK, Salah Z, Maly B, Smith Y, Tufail R, Abu-Odeh M, Zanesi N, Croce CM, Nawaz Z, Aqeilan RI. Abdeen SK, et al. Among authors: aqeilan ri. Oncogene. 2011 Sep 8;30(36):3900-6. doi: 10.1038/onc.2011.115. Epub 2011 Apr 18. Oncogene. 2011. PMID: 21499303
WWOX guards genome stability by activating ATM.
Hazan I, Abu-Odeh M, Hofmann TG, Aqeilan RI. Hazan I, et al. Mol Cell Oncol. 2015 Feb 23;2(4):e1008288. doi: 10.1080/23723556.2015.1008288. eCollection 2015 Oct-Dec. Mol Cell Oncol. 2015. PMID: 27308504 Free PMC article.
WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma.
Del Mare S, Husanie H, Iancu O, Abu-Odeh M, Evangelou K, Lovat F, Volinia S, Gordon J, Amir G, Stein J, Stein GS, Croce CM, Gorgoulis V, Lian JB, Aqeilan RI. Del Mare S, et al. Cancer Res. 2016 Oct 15;76(20):6107-6117. doi: 10.1158/0008-5472.CAN-16-0621. Epub 2016 Aug 22. Cancer Res. 2016. PMID: 27550453 Free PMC article.
TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells.
Gershkovitz M, Caspi Y, Fainsod-Levi T, Katz B, Michaeli J, Khawaled S, Lev S, Polyansky L, Shaul ME, Sionov RV, Cohen-Daniel L, Aqeilan RI, Shaul YD, Mori Y, Karni R, Fridlender ZG, Binshtok AM, Granot Z. Gershkovitz M, et al. Among authors: aqeilan ri. Cancer Res. 2018 May 15;78(10):2680-2690. doi: 10.1158/0008-5472.CAN-17-3614. Epub 2018 Feb 28. Cancer Res. 2018. PMID: 29490946
Pleiotropic tumor suppressor functions of WWOX antagonize metastasis.
Khawaled S, Nigita G, Distefano R, Oster S, Suh SS, Smith Y, Khalaileh A, Peng Y, Croce CM, Geiger T, Seewaldt VL, Aqeilan RI. Khawaled S, et al. Among authors: aqeilan ri. Signal Transduct Target Ther. 2020 Apr 17;5(1):43. doi: 10.1038/s41392-020-0136-8. Signal Transduct Target Ther. 2020. PMID: 32300104 Free PMC article.
144 results