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Page 1
Investigation of Copy Number Variation in South African Patients With Congenital Heart Defects.
Saacks NA, Eales J, Spracklen TF, Aldersley T, Human P, Verryn M, Lawrenson J, Cupido B, Comitis G, De Decker R, Fourie B, Swanson L, Joachim A, Brooks A, Ramesar R, Shaboodien G, Keavney BD, Zühlke LJ. Saacks NA, et al. Among authors: eales j. Circ Genom Precis Med. 2022 Dec;15(6):e003510. doi: 10.1161/CIRCGEN.121.003510. Epub 2022 Oct 7. Circ Genom Precis Med. 2022. PMID: 36205932 Free PMC article.
Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis.
Eales JM, Maan AA, Xu X, Michoel T, Hallast P, Batini C, Zadik D, Prestes PR, Molina E, Denniff M, Schroeder J, Bjorkegren JLM, Thompson J, Maffia P, Guzik TJ, Keavney B, Jobling MA, Samani NJ, Charchar FJ, Tomaszewski M. Eales JM, et al. Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2386-2401. doi: 10.1161/ATVBAHA.119.312405. Epub 2019 Sep 5. Arterioscler Thromb Vasc Biol. 2019. PMID: 31644355 Free PMC article.
Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney.
Jiang X, Eales JM, Scannali D, Nazgiewicz A, Prestes P, Maier M, Denniff M, Xu X, Saluja S, Cano-Gamez E, Wystrychowski W, Szulinska M, Antczak A, Byars S, Skrypnik D, Glyda M, Król R, Zywiec J, Zukowska-Szczechowska E, Burrell LM, Woolf AS, Greenstein A, Bogdanski P, Keavney B, Morris AP, Heagerty A, Williams B, Harrap SB, Trynka G, Samani NJ, Guzik TJ, Charchar FJ, Tomaszewski M. Jiang X, et al. Among authors: eales jm. Eur Heart J. 2020 Dec 21;41(48):4580-4588. doi: 10.1093/eurheartj/ehaa794. Eur Heart J. 2020. PMID: 33206176 Free PMC article.
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney.
Eales JM, Jiang X, Xu X, Saluja S, Akbarov A, Cano-Gamez E, McNulty MT, Finan C, Guo H, Wystrychowski W, Szulinska M, Thomas HB, Pramanik S, Chopade S, Prestes PR, Wise I, Evangelou E, Salehi M, Shakanti Y, Ekholm M, Denniff M, Nazgiewicz A, Eichinger F, Godfrey B, Antczak A, Glyda M, Król R, Eyre S, Brown J, Berzuini C, Bowes J, Caulfield M, Zukowska-Szczechowska E, Zywiec J, Bogdanski P, Kretzler M, Woolf AS, Talavera D, Keavney B, Maffia P, Guzik TJ, O'Keefe RT, Trynka G, Samani NJ, Hingorani A, Sampson MG, Morris AP, Charchar FJ, Tomaszewski M. Eales JM, et al. Nat Genet. 2021 May;53(5):630-637. doi: 10.1038/s41588-021-00835-w. Epub 2021 May 6. Nat Genet. 2021. PMID: 33958779
Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets.
Xu X, Khunsriraksakul C, Eales JM, Rubin S, Scannali D, Saluja S, Talavera D, Markus H, Wang L, Drzal M, Maan A, Lay AC, Prestes PR, Regan J, Diwadkar AR, Denniff M, Rempega G, Ryszawy J, Król R, Dormer JP, Szulinska M, Walczak M, Antczak A, Matías-García PR, Waldenberger M, Woolf AS, Keavney B, Zukowska-Szczechowska E, Wystrychowski W, Zywiec J, Bogdanski P, Danser AHJ, Samani NJ, Guzik TJ, Morris AP, Liu DJ, Charchar FJ; Human Kidney Tissue Resource Study Group; Tomaszewski M. Xu X, et al. Among authors: eales jm. Nat Commun. 2024 Mar 19;15(1):2359. doi: 10.1038/s41467-024-46132-y. Nat Commun. 2024. PMID: 38504097 Free PMC article.
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, Liu DJ, Prins BP, Stewart ID, Cabrera CP, Eales JM, Akbarov A, Auer PL, Bielak LF, Bis JC, Braithwaite VS, Brody JA, Daw EW, Warren HR, Drenos F, Nielsen SF, Faul JD, Fauman EB, Fava C, Ferreira T, Foley CN, Franceschini N, Gao H, Giannakopoulou O, Giulianini F, Gudbjartsson DF, Guo X, Harris SE, Havulinna AS, Helgadottir A, Huffman JE, Hwang SJ, Kanoni S, Kontto J, Larson MG, Li-Gao R, Lindström J, Lotta LA, Lu Y, Luan J, Mahajan A, Malerba G, Masca NGD, Mei H, Menni C, Mook-Kanamori DO, Mosen-Ansorena D, Müller-Nurasyid M, Paré G, Paul DS, Perola M, Poveda A, Rauramaa R, Richard M, Richardson TG, Sepúlveda N, Sim X, Smith AV, Smith JA, Staley JR, Stanáková A, Sulem P, Thériault S, Thorsteinsdottir U, Trompet S, Varga TV, Velez Edwards DR, Veronesi G, Weiss S, Willems SM, Yao J, Young R, Yu B, Zhang W, Zhao JH, Zhao W, Zhao W, Evangelou E, Aeschbacher S, Asllanaj E, Blankenberg S, Bonnycastle LL, Bork-Jensen J, Brandslund I, Braund PS, Burgess S, Cho K, Christensen C, Connell J, Mutsert R, Dominiczak AF,… See abstract for full author list ➔ Surendran P, et al. Among authors: eales jm. Nat Genet. 2020 Dec;52(12):1314-1332. doi: 10.1038/s41588-020-00713-x. Epub 2020 Nov 23. Nat Genet. 2020. PMID: 33230300 Free PMC article.
Genetic variation within the Y chromosome is not associated with histological characteristics of the atherosclerotic carotid artery or aneurysmal wall.
Haitjema S, van Setten J, Eales J, van der Laan SW, Gandin I, de Vries JP, de Borst GJ, Pasterkamp G, Asselbergs FW, Charchar FJ, Wilson JF, de Jager SC, Tomaszewski M, den Ruijter HM. Haitjema S, et al. Among authors: eales j. Atherosclerosis. 2017 Apr;259:114-119. doi: 10.1016/j.atherosclerosis.2017.02.011. Epub 2017 Feb 20. Atherosclerosis. 2017. PMID: 28238413 Free article.
Telomere therapy for chronic kidney disease.
Akinnibosun OA, Maier MC, Eales J, Tomaszewski M, Charchar FJ. Akinnibosun OA, et al. Among authors: eales j. Epigenomics. 2022 Sep;14(17):1039-1054. doi: 10.2217/epi-2022-0073. Epub 2022 Sep 30. Epigenomics. 2022. PMID: 36177720 Review.
Male-specific region of the Y chromosome and cardiovascular risk: phylogenetic analysis and gene expression studies.
Bloomer LD, Nelson CP, Eales J, Denniff M, Christofidou P, Debiec R, Moore J; Cardiogenics Consortium; Zukowska-Szczechowska E, Goodall AH, Thompson J, Samani NJ, Charchar FJ, Tomaszewski M. Bloomer LD, et al. Among authors: eales j. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1722-7. doi: 10.1161/ATVBAHA.113.301608. Epub 2013 May 2. Arterioscler Thromb Vasc Biol. 2013. PMID: 23640493
Renal Mechanisms of Association between Fibroblast Growth Factor 1 and Blood Pressure.
Tomaszewski M, Eales J, Denniff M, Myers S, Chew GS, Nelson CP, Christofidou P, Desai A, Büsst C, Wojnar L, Musialik K, Jozwiak J, Debiec R, Dominiczak AF, Navis G, van Gilst WH, van der Harst P, Samani NJ, Harrap S, Bogdanski P, Zukowska-Szczechowska E, Charchar FJ. Tomaszewski M, et al. Among authors: eales j. J Am Soc Nephrol. 2015 Dec;26(12):3151-60. doi: 10.1681/ASN.2014121211. Epub 2015 Apr 27. J Am Soc Nephrol. 2015. PMID: 25918036 Free PMC article.
170 results