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A 6-month systems toxicology inhalation study in ApoE-/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke.
Szostak J, Wong ET, Titz B, Lee T, Wong SK, Low T, Lee KM, Zhang J, Kumar A, Schlage WK, Guedj E, Phillips B, Leroy P, Buettner A, Xiang Y, Martin F, Sewer A, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Szostak J, et al. Among authors: kuczaj a. Am J Physiol Heart Circ Physiol. 2020 Mar 1;318(3):H604-H631. doi: 10.1152/ajpheart.00613.2019. Epub 2020 Jan 24. Am J Physiol Heart Circ Physiol. 2020. PMID: 31975625 Free article.
Alternatives to Animal Use in Risk Assessment of Mixtures.
Wallace Hayes A, Muriana A, Alzualde A, Fernandez DB, Iskandar A, Peitsch MC, Kuczaj A, Hoeng J. Wallace Hayes A, et al. Among authors: kuczaj a. Int J Toxicol. 2020 Mar/Apr;39(2):165-172. doi: 10.1177/1091581820905088. Epub 2020 Feb 18. Int J Toxicol. 2020. PMID: 32066298 Review.
E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE-/- mouse model.
Reumann MK, Schaefer J, Titz B, Aspera-Werz RH, Wong ET, Szostak J, Häussling V, Ehnert S, Leroy P, Tan WT, Kuczaj A, Audretsch C, Springer F, Badke A, Augat P, Quentanilla-Fend L, Martella M, Lee KM, Peitsch MC, Hoeng J, Nussler AK. Reumann MK, et al. Among authors: kuczaj a. Arch Toxicol. 2020 Jun;94(6):2163-2177. doi: 10.1007/s00204-020-02769-4. Epub 2020 May 14. Arch Toxicol. 2020. PMID: 32409933 Free PMC article.
In Vivo Profiling of a Natural Alkaloid, Anatabine, in Rodents: Pharmacokinetics and Anti-Inflammatory Efficacy.
Xia W, Kolli AR, Koshibu K, Martin F, Kondylis A, Kuczaj A, Tan WT, Yeo YS, Tan G, Teng C, Woon K, Schneider T, Talikka M, Phillips BW, Vanscheeuwijck P, Peitsch MC, Hoeng J. Xia W, et al. Among authors: kuczaj a. J Nat Prod. 2021 Apr 23;84(4):1012-1021. doi: 10.1021/acs.jnatprod.0c01044. Epub 2021 Mar 11. J Nat Prod. 2021. PMID: 33706515 Free article.
67 results