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Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung.
Reyes NS, Krasilnikov M, Allen NC, Lee JY, Hyams B, Zhou M, Ravishankar S, Cassandras M, Wang C, Khan I, Matatia P, Johmura Y, Molofsky A, Matthay M, Nakanishi M, Sheppard D, Campisi J, Peng T. Reyes NS, et al. Among authors: sheppard d. Science. 2022 Oct 14;378(6616):192-201. doi: 10.1126/science.abf3326. Epub 2022 Oct 13. Science. 2022. PMID: 36227993 Free PMC article.
TGF-beta is a critical mediator of acute lung injury.
Pittet JF, Griffiths MJ, Geiser T, Kaminski N, Dalton SL, Huang X, Brown LA, Gotwals PJ, Koteliansky VE, Matthay MA, Sheppard D. Pittet JF, et al. Among authors: sheppard d. J Clin Invest. 2001 Jun;107(12):1537-44. doi: 10.1172/JCI11963. J Clin Invest. 2001. PMID: 11413161 Free PMC article.
Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism.
Frank J, Roux J, Kawakatsu H, Su G, Dagenais A, Berthiaume Y, Howard M, Canessa CM, Fang X, Sheppard D, Matthay MA, Pittet JF. Frank J, et al. Among authors: sheppard d. J Biol Chem. 2003 Nov 7;278(45):43939-50. doi: 10.1074/jbc.M304882200. Epub 2003 Aug 20. J Biol Chem. 2003. PMID: 12930837 Free article.
IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia.
Bhattacharya M, Su G, Su X, Oses-Prieto JA, Li JT, Huang X, Hernandez H, Atakilit A, Burlingame AL, Matthay MA, Sheppard D. Bhattacharya M, et al. Among authors: sheppard d. Am J Physiol Lung Cell Mol Physiol. 2012 Jul 1;303(1):L12-9. doi: 10.1152/ajplung.00375.2011. Epub 2012 May 4. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22561460 Free PMC article.
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome.
Li JT, Melton AC, Su G, Hamm DE, LaFemina M, Howard J, Fang X, Bhat S, Huynh KM, O'Kane CM, Ingram RJ, Muir RR, McAuley DF, Matthay MA, Sheppard D. Li JT, et al. Among authors: sheppard d. J Immunol. 2015 Jul 1;195(1):87-95. doi: 10.4049/jimmunol.1500054. Epub 2015 May 22. J Immunol. 2015. PMID: 26002979 Free PMC article.
899 results