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Page 1
GPC3-Unc5 receptor complex structure and role in cell migration.
Akkermans O, Delloye-Bourgeois C, Peregrina C, Carrasquero-Ordaz M, Kokolaki M, Berbeira-Santana M, Chavent M, Reynaud F, Raj R, Agirre J, Aksu M, White ES, Lowe E, Ben Amar D, Zaballa S, Huo J, Pakos I, McCubbin PTN, Comoletti D, Owens RJ, Robinson CV, Castellani V, Del Toro D, Seiradake E. Akkermans O, et al. Among authors: huo j. Cell. 2022 Oct 13;185(21):3931-3949.e26. doi: 10.1016/j.cell.2022.09.025. Cell. 2022. PMID: 36240740 Free PMC article.
Structural basis of antifolate recognition and transport by PCFT.
Parker JL, Deme JC, Kuteyi G, Wu Z, Huo J, Goldman ID, Owens RJ, Biggin PC, Lea SM, Newstead S. Parker JL, et al. Among authors: huo j. Nature. 2021 Jul;595(7865):130-134. doi: 10.1038/s41586-021-03579-z. Epub 2021 May 26. Nature. 2021. PMID: 34040256 Free PMC article.
Architecture of cell-cell junctions in situ reveals a mechanism for bacterial biofilm inhibition.
Melia CE, Bolla JR, Katharios-Lanwermeyer S, Mihaylov DB, Hoffmann PC, Huo J, Wozny MR, Elfari LM, Böhning J, Morgan AN, Hitchman CJ, Owens RJ, Robinson CV, O'Toole GA, Bharat TAM. Melia CE, et al. Among authors: huo j. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2109940118. doi: 10.1073/pnas.2109940118. Proc Natl Acad Sci U S A. 2021. PMID: 34321357 Free PMC article.
The use of nanobodies in a sensitive ELISA test for SARS-CoV-2 Spike 1 protein.
Girt GC, Lakshminarayanan A, Huo J, Dormon J, Norman C, Afrough B, Harding A, James W, Owens RJ, Naismith JH. Girt GC, et al. Among authors: huo j. R Soc Open Sci. 2021 Sep 30;8(9):211016. doi: 10.1098/rsos.211016. eCollection 2021 Sep. R Soc Open Sci. 2021. PMID: 34631127 Free PMC article.
SARS-CoV-2 triggers pericyte-mediated cerebral capillary constriction.
Hirunpattarasilp C, James G, Kwanthongdee J, Freitas F, Huo J, Sethi H, Kittler JT, Owens RJ, McCoy LE, Attwell D. Hirunpattarasilp C, et al. Among authors: huo j. Brain. 2023 Feb 13;146(2):727-738. doi: 10.1093/brain/awac272. Brain. 2023. PMID: 35867861 Free PMC article.
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.
Huo J, Le Bas A, Ruza RR, Duyvesteyn HME, Mikolajek H, Malinauskas T, Tan TK, Rijal P, Dumoux M, Ward PN, Ren J, Zhou D, Harrison PJ, Weckener M, Clare DK, Vogirala VK, Radecke J, Moynié L, Zhao Y, Gilbert-Jaramillo J, Knight ML, Tree JA, Buttigieg KR, Coombes N, Elmore MJ, Carroll MW, Carrique L, Shah PNM, James W, Townsend AR, Stuart DI, Owens RJ, Naismith JH. Huo J, et al. Nat Struct Mol Biol. 2020 Sep;27(9):846-854. doi: 10.1038/s41594-020-0469-6. Epub 2020 Jul 13. Nat Struct Mol Biol. 2020. PMID: 32661423
A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Huo J, Mikolajek H, Le Bas A, Clark JJ, Sharma P, Kipar A, Dormon J, Norman C, Weckener M, Clare DK, Harrison PJ, Tree JA, Buttigieg KR, Salguero FJ, Watson R, Knott D, Carnell O, Ngabo D, Elmore MJ, Fotheringham S, Harding A, Moynié L, Ward PN, Dumoux M, Prince T, Hall Y, Hiscox JA, Owen A, James W, Carroll MW, Stewart JP, Naismith JH, Owens RJ. Huo J, et al. Nat Commun. 2021 Sep 22;12(1):5469. doi: 10.1038/s41467-021-25480-z. Nat Commun. 2021. PMID: 34552091 Free PMC article.
Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.
Mikolajek H, Weckener M, Brotzakis ZF, Huo J, Dalietou EV, Le Bas A, Sormanni P, Harrison PJ, Ward PN, Truong S, Moynie L, Clare DK, Dumoux M, Dormon J, Norman C, Hussain N, Vogirala V, Owens RJ, Vendruscolo M, Naismith JH. Mikolajek H, et al. Among authors: huo j. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2205412119. doi: 10.1073/pnas.2205412119. Epub 2022 Jul 15. Proc Natl Acad Sci U S A. 2022. PMID: 35858383 Free PMC article.
1,851 results