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Hindbrain insulin controls feeding behavior.
Eerola K, Longo F, Reinbothe TM, Richard JE, Shevchouk OT, López-Ferreras L, Mishra D, Asker M, Tolö J, Miranda C, Musovic S, Olofsson CS, Rorsman P, Skibicka KP. Eerola K, et al. Among authors: reinbothe tm. Mol Metab. 2022 Dec;66:101614. doi: 10.1016/j.molmet.2022.101614. Epub 2022 Oct 13. Mol Metab. 2022. PMID: 36244663 Free PMC article.
Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes.
Rosengren AH, Jokubka R, Tojjar D, Granhall C, Hansson O, Li DQ, Nagaraj V, Reinbothe TM, Tuncel J, Eliasson L, Groop L, Rorsman P, Salehi A, Lyssenko V, Luthman H, Renström E. Rosengren AH, et al. Among authors: reinbothe tm. Science. 2010 Jan 8;327(5962):217-20. doi: 10.1126/science.1176827. Epub 2009 Nov 19. Science. 2010. PMID: 19965390
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
Mahdi T, Hänzelmann S, Salehi A, Muhammed SJ, Reinbothe TM, Tang Y, Axelsson AS, Zhou Y, Jing X, Almgren P, Krus U, Taneera J, Blom AM, Lyssenko V, Esguerra JL, Hansson O, Eliasson L, Derry J, Zhang E, Wollheim CB, Groop L, Renström E, Rosengren AH. Mahdi T, et al. Among authors: reinbothe tm. Cell Metab. 2012 Nov 7;16(5):625-33. doi: 10.1016/j.cmet.2012.10.009. Cell Metab. 2012. PMID: 23140642 Free article.
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
Shigeto M, Ramracheya R, Tarasov AI, Cha CY, Chibalina MV, Hastoy B, Philippaert K, Reinbothe T, Rorsman N, Salehi A, Sones WR, Vergari E, Weston C, Gorelik J, Katsura M, Nikolaev VO, Vennekens R, Zaccolo M, Galione A, Johnson PR, Kaku K, Ladds G, Rorsman P. Shigeto M, et al. J Clin Invest. 2015 Dec;125(12):4714-28. doi: 10.1172/JCI81975. Epub 2015 Nov 16. J Clin Invest. 2015. PMID: 26571400 Free PMC article.
Optogenetic Control of Pancreatic Islets.
Reinbothe TM, Mollet IG. Reinbothe TM, et al. Methods Mol Biol. 2016;1408:107-23. doi: 10.1007/978-1-4939-3512-3_8. Methods Mol Biol. 2016. PMID: 26965119
16 results