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Genomic Stratification of Clozapine Prescription Patterns Using Schizophrenia Polygenic Scores.
Kappel DB, Legge SE, Hubbard L, Willcocks IR, O'Connell KS, Smith RL, Molden E, Andreassen OA, King A, Jansen J, Helthuis M, Owen MJ, O'Donovan MC, Walters JTR, Pardiñas AF. Kappel DB, et al. Biol Psychiatry. 2023 Jan 15;93(2):149-156. doi: 10.1016/j.biopsych.2022.07.014. Epub 2022 Aug 5. Biol Psychiatry. 2023. PMID: 36244804 Free PMC article.
Dissecting the cross-trait effects of the FOXP2 GWAS hit on clinical and brain phenotypes in adults with ADHD.
Meyer GP, da Silva BS, Bandeira CE, Tavares MEA, Cupertino RB, Oliveira EP, Müller D, Kappel DB, Teche SP, Vitola ES, Rohde LA, Rovaris DL, Grevet EH, Bau CHD. Meyer GP, et al. Among authors: kappel db. Eur Arch Psychiatry Clin Neurosci. 2023 Feb;273(1):15-24. doi: 10.1007/s00406-022-01388-7. Epub 2022 Mar 12. Eur Arch Psychiatry Clin Neurosci. 2023. PMID: 35279744
Further replication of the synergistic interaction between LPHN3 and the NTAD gene cluster on ADHD and its clinical course throughout adulthood.
Kappel DB, Schuch JB, Rovaris DL, da Silva BS, Cupertino RB, Winkler C, Teche SP, Vitola ES, Karam RG, Rohde LA, Bau CHD, Grevet EH, Mota NR. Kappel DB, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):120-127. doi: 10.1016/j.pnpbp.2017.06.011. Epub 2017 Jun 15. Prog Neuropsychopharmacol Biol Psychiatry. 2017. PMID: 28624582 Free article.
The association between SYT1-rs2251214 and cocaine use disorder further supports its role in psychiatry.
da Silva BS, Cupertino RB, Schuch JB, Kappel DB, Sanvicente-Vieira B, Bandeira CE, von Diemen L, Kessler FHP, Grevet EH, Grassi-Oliveira R, Bau CHD, Rovaris DL. da Silva BS, et al. Among authors: kappel db. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Aug 30;94:109642. doi: 10.1016/j.pnpbp.2019.109642. Epub 2019 May 3. Prog Neuropsychopharmacol Biol Psychiatry. 2019. PMID: 31059723 Free article.
Exocytosis-related genes and response to methylphenidate treatment in adults with ADHD.
da Silva BS, Cupertino RB, Rovaris DL, Schuch JB, Kappel DB, Müller D, Bandeira CE, Victor MM, Karam RG, Mota NR, Rohde LA, Contini V, Grevet EH, Bau CHD. da Silva BS, et al. Among authors: kappel db. Mol Psychiatry. 2018 Jun;23(6):1446-1452. doi: 10.1038/mp.2017.90. Epub 2017 May 2. Mol Psychiatry. 2018. PMID: 28461697
Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility.
Bruxel EM, Moreira-Maia CR, Akutagava-Martins GC, Quinn TP, Klein M, Franke B, Ribasés M, Rovira P, Sánchez-Mora C, Kappel DB, Mota NR, Grevet EH, Bau CHD, Arcos-Burgos M, Rohde LA, Hutz MH. Bruxel EM, et al. Among authors: kappel db. Mol Psychiatry. 2021 Jun;26(6):2277-2285. doi: 10.1038/s41380-020-0673-0. Epub 2020 Feb 12. Mol Psychiatry. 2021. PMID: 32051549
Replicated association of Synaptotagmin (SYT1) with ADHD and its broader influence in externalizing behaviors.
Cupertino RB, Schuch JB, Bandeira CE, da Silva BS, Rovaris DL, Kappel DB, Contini V, Salatino-Oliveira A, Vitola ES, Karam RG, Hutz MH, Rohde LA, Grevet EH, Bau CHD, Mota NR. Cupertino RB, et al. Among authors: kappel db. Eur Neuropsychopharmacol. 2017 Mar;27(3):239-247. doi: 10.1016/j.euroneuro.2017.01.007. Epub 2017 Jan 24. Eur Neuropsychopharmacol. 2017. PMID: 28130000
Evidence of sexual dimorphism of HTR1B gene on major adult ADHD comorbidities.
Müller D, Grevet EH, Panzenhagen AC, Cupertino RB, da Silva BS, Kappel DB, Mota NR, Blaya-Rocha P, Teche SP, Vitola ES, Rohde LA, Contini V, Rovaris DL, Schuch JB, Bau CHD. Müller D, et al. Among authors: kappel db. J Psychiatr Res. 2017 Dec;95:269-275. doi: 10.1016/j.jpsychires.2017.09.011. Epub 2017 Sep 8. J Psychiatr Res. 2017. PMID: 28923721
23 results