Laudon H - Search Results

1

Lecanemab, Aducanumab, and Gantenerumab - Binding Profiles to Different Forms of Amyloid-Beta Might Explain Efficacy and Side Effects in Clinical Trials for Alzheimer's Disease.

Söderberg L, Johannesson M, Nygren P, Laudon H, Eriksson F, Osswald G, Möller C, Lannfelt L. Söderberg L, et al. Among authors: laudon h. Neurotherapeutics. 2023 Jan;20(1):195-206. doi: 10.1007/s13311-022-01308-6. Epub 2022 Oct 17. Neurotherapeutics. 2023. PMID: 36253511 Free PMC article.

2

APP intracellular domain formation and unaltered signaling in the presence of familial Alzheimer's disease mutations.

Bergman A, Religa D, Karlström H, Laudon H, Winblad B, Lannfelt L, Lundkvist J, Näslund J. Bergman A, et al. Among authors: laudon h. Exp Cell Res. 2003 Jul 1;287(1):1-9. doi: 10.1016/s0014-4827(03)00117-4. Exp Cell Res. 2003. PMID: 12799176

3

The murine version of BAN2401 (mAb158) selectively reduces amyloid-β protofibrils in brain and cerebrospinal fluid of tg-ArcSwe mice.

Tucker S, Möller C, Tegerstedt K, Lord A, Laudon H, Sjödahl J, Söderberg L, Spens E, Sahlin C, Waara ER, Satlin A, Gellerfors P, Osswald G, Lannfelt L. Tucker S, et al. Among authors: laudon h. J Alzheimers Dis. 2015;43(2):575-88. doi: 10.3233/JAD-140741. J Alzheimers Dis. 2015. PMID: 25096615

4

Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.

Syvänen S, Hultqvist G, Gustavsson T, Gumucio A, Laudon H, Söderberg L, Ingelsson M, Lannfelt L, Sehlin D. Syvänen S, et al. Among authors: laudon h. Alzheimers Res Ther. 2018 May 24;10(1):49. doi: 10.1186/s13195-018-0377-8. Alzheimers Res Ther. 2018. PMID: 29793530 Free PMC article.

5

Long-term effects of immunotherapy with a brain penetrating Aβ antibody in a mouse model of Alzheimer's disease.

Gustavsson T, Metzendorf NG, Wik E, Roshanbin S, Julku U, Chourlia A, Nilsson P, Andersson KG, Laudon H, Hultqvist G, Syvänen S, Sehlin D. Gustavsson T, et al. Among authors: laudon h. Alzheimers Res Ther. 2023 May 2;15(1):90. doi: 10.1186/s13195-023-01236-3. Alzheimers Res Ther. 2023. PMID: 37131196 Free PMC article.

6

Amyloid beta pathology in Alzheimer's disease and schizophrenia.

Religa D, Laudon H, Styczynska M, Winblad B, Näslund J, Haroutunian V. Religa D, et al. Among authors: laudon h. Am J Psychiatry. 2003 May;160(5):867-72. doi: 10.1176/appi.ajp.160.5.867. Am J Psychiatry. 2003. PMID: 12727689

7

Presenilin-1 mutation L271V results in altered exon 8 splicing and Alzheimer's disease with non-cored plaques and no neuritic dystrophy.

Kwok JB, Halliday GM, Brooks WS, Dolios G, Laudon H, Murayama O, Hallupp M, Badenhop RF, Vickers J, Wang R, Naslund J, Takashima A, Gandy SE, Schofield PR. Kwok JB, et al. Among authors: laudon h. J Biol Chem. 2003 Feb 28;278(9):6748-54. doi: 10.1074/jbc.M211827200. Epub 2002 Dec 19. J Biol Chem. 2003. PMID: 12493737 Free article.

8

Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein.

Laudon H, Mathews PM, Karlström H, Bergman A, Farmery MR, Nixon RA, Winblad B, Gandy SE, Lendahl U, Lundkvist J, Näslund J. Laudon H, et al. J Neurochem. 2004 Apr;89(1):44-53. doi: 10.1046/j.1471-4159.2003.02298.x. J Neurochem. 2004. PMID: 15030388 Free article.

9

Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis.

Laudon H, Karlström H, Mathews PM, Farmery MR, Gandy SE, Lundkvist J, Lendahl U, Näslund J. Laudon H, et al. J Biol Chem. 2004 Jun 4;279(23):23925-32. doi: 10.1074/jbc.M401277200. Epub 2004 Mar 29. J Biol Chem. 2004. PMID: 15051718 Free article.

10

The extreme C terminus of presenilin 1 is essential for gamma-secretase complex assembly and activity.

Bergman A, Laudon H, Winblad B, Lundkvist J, Näslund J. Bergman A, et al. Among authors: laudon h. J Biol Chem. 2004 Oct 29;279(44):45564-72. doi: 10.1074/jbc.M407717200. Epub 2004 Aug 20. J Biol Chem. 2004. PMID: 15322123 Free article.

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