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Parallel detection of SARS-CoV-2 epitopes reveals dynamic immunodominance profiles of CD8+ T memory cells in convalescent COVID-19 donors.
van den Dijssel J, Hagen RR, de Jongh R, Steenhuis M, Rispens T, Geerdes DM, Mok JY, Kragten AH, Duurland MC, Verstegen NJ, van Ham SM, van Esch WJ, van Gisbergen KP, Hombrink P, Ten Brinke A, van de Sandt CE. van den Dijssel J, et al. Among authors: van gisbergen kp. Clin Transl Immunology. 2022 Oct 14;11(10):e1423. doi: 10.1002/cti2.1423. eCollection 2022. Clin Transl Immunology. 2022. PMID: 36254196 Free PMC article.
The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants.
van Gisbergen KP, Klarenbeek PL, Kragten NA, Unger PP, Nieuwenhuis MB, Wensveen FM, ten Brinke A, Tak PP, Eldering E, Nolte MA, van Lier RA. van Gisbergen KP, et al. Among authors: van lier ra. Immunity. 2011 Jul 22;35(1):97-108. doi: 10.1016/j.immuni.2011.04.020. Epub 2011 Jul 14. Immunity. 2011. PMID: 21763160 Free article.
Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology.
Wensveen FM, Klarenbeek PL, van Gisbergen KP, Pascutti MF, Derks IA, van Schaik BD, Ten Brinke A, de Vries N, Cekinovic D, Jonjic S, van Lier RA, Eldering E. Wensveen FM, et al. Among authors: van lier ra, van gisbergen kp, van schaik bd. J Immunol. 2013 Feb 1;190(3):1180-91. doi: 10.4049/jimmunol.1202304. Epub 2012 Dec 31. J Immunol. 2013. PMID: 23277490
A central role for Notch in effector CD8(+) T cell differentiation.
Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF, ten Brinke A, Willemsen AM, van Kampen AH, Kaech SM, Blander JM, van Gisbergen K, Amsen D. Backer RA, et al. Nat Immunol. 2014 Dec;15(12):1143-51. doi: 10.1038/ni.3027. Epub 2014 Oct 26. Nat Immunol. 2014. PMID: 25344724 Free PMC article.
The Transcription Factor Hobit Identifies Human Cytotoxic CD4+ T Cells.
Oja AE, Vieira Braga FA, Remmerswaal EB, Kragten NA, Hertoghs KM, Zuo J, Moss PA, van Lier RA, van Gisbergen KP, Hombrink P. Oja AE, et al. Among authors: van lier ra, van gisbergen kp. Front Immunol. 2017 Mar 24;8:325. doi: 10.3389/fimmu.2017.00325. eCollection 2017. Front Immunol. 2017. PMID: 28392788 Free PMC article.
Peripheral and systemic antigens elicit an expandable pool of resident memory CD8+ T cells in the bone marrow.
Pascutti MF, Geerman S, Collins N, Brasser G, Nota B, Stark R, Behr F, Oja A, Slot E, Panagioti E, Prier JE, Hickson S, Wolkers MC, Heemskerk MHM, Hombrink P, Arens R, Mackay LK, van Gisbergen KPJM, Nolte MA. Pascutti MF, et al. Eur J Immunol. 2019 Jun;49(6):853-872. doi: 10.1002/eji.201848003. Epub 2019 Apr 2. Eur J Immunol. 2019. PMID: 30891737 Free PMC article.
63 results