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Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis.
Edavettal S, Cejudo-Martin P, Dasgupta B, Yang D, Buschman MD, Domingo D, Van Kolen K, Jaiprasat P, Gordon R, Schutsky K, Geist B, Taylor N, Soubrane CH, Van Der Helm E, LaCombe A, Ainekulu Z, Lacy E, Aligo J, Ho J, He Y, Lebowitz PF, Patterson JT, Scheer JM, Singh S. Edavettal S, et al. Among authors: van der helm e. Med. 2022 Dec 9;3(12):860-882.e15. doi: 10.1016/j.medj.2022.09.007. Epub 2022 Oct 17. Med. 2022. PMID: 36257298 Free article.
Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series.
McGowan D, Vendeville S, Lin TI, Tahri A, Hu L, Cummings MD, Amssoms K, Berke JM, Canard M, Cleiren E, Dehertogh P, Last S, Fransen E, Van Der Helm E, Van den Steen I, Vijgen L, Rouan MC, Fanning G, Nyanguile O, Van Emelen K, Simmen K, Raboisson P. McGowan D, et al. Among authors: van der helm e, van den steen i, van emelen k. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4431-6. doi: 10.1016/j.bmcl.2012.03.097. Epub 2012 Apr 3. Bioorg Med Chem Lett. 2012. PMID: 22542193
Engineered phage with antibacterial CRISPR-Cas selectively reduce E. coli burden in mice.
Gencay YE, Jasinskytė D, Robert C, Semsey S, Martínez V, Petersen AØ, Brunner K, de Santiago Torio A, Salazar A, Turcu IC, Eriksen MK, Koval L, Takos A, Pascal R, Schou TS, Bayer L, Bryde T, Johansen KC, Bak EG, Smrekar F, Doyle TB, Satlin MJ, Gram A, Carvalho J, Jessen L, Hallström B, Hink J, Damholt B, Troy A, Grove M, Clube J, Grøndahl C, Haaber JK, van der Helm E, Zdravkovic M, Sommer MOA. Gencay YE, et al. Among authors: van der helm e. Nat Biotechnol. 2024 Feb;42(2):265-274. doi: 10.1038/s41587-023-01759-y. Epub 2023 May 4. Nat Biotechnol. 2024. PMID: 37142704 Free PMC article.
A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics.
Malla S, van der Helm E, Darbani B, Wieschalka S, Förster J, Borodina I, Sommer MOA. Malla S, et al. Among authors: van der helm e. Front Microbiol. 2022 Apr 14;13:855736. doi: 10.3389/fmicb.2022.855736. eCollection 2022. Front Microbiol. 2022. PMID: 35495724 Free PMC article.
Corrigendum to "Antibiotic Treatment Drives the Diversification of the Human Gut Resistome" [Genomics Proteomics Bioinformatics 17 (1) (2019) 39-51].
Li J, Rettedal EA, van der Helm E, Ellabaan M, Panagiotou G, Sommer MOA. Li J, et al. Among authors: van der helm e. Genomics Proteomics Bioinformatics. 2020 Oct;18(5):624-625. doi: 10.1016/j.gpb.2020.07.002. Epub 2020 Sep 9. Genomics Proteomics Bioinformatics. 2020. PMID: 32917572 Free PMC article. No abstract available.
Corrigendum to: Metagenomic analysis of planktonic riverine microbial consortia using nanopore sequencing reveals insight into river microbe taxonomy and function.
Reddington K, Eccles D, O'Grady J, Drown DM, Hansen LH, Nielsen TK, Ducluzeau AL, Leggett RM, Heavens D, Peel N, Snutch TP, Bayega A, Oikonomopoulos S, Ragoussis I, Barry T, van der Helm E, Jolic D, Richardson H, Jansen H, Tyson JR, Jain M, Brown BL. Reddington K, et al. Among authors: van der helm e. Gigascience. 2020 Jun 1;9(6):giaa074. doi: 10.1093/gigascience/giaa074. Gigascience. 2020. PMID: 32578857 Free PMC article. No abstract available.
Metagenomic analysis of planktonic riverine microbial consortia using nanopore sequencing reveals insight into river microbe taxonomy and function.
Reddington K, Eccles D, O'Grady J, Drown DM, Hansen LH, Nielsen TK, Ducluzeau AL, Leggett RM, Heavens D, Peel N, Snutch TP, Bayega A, Oikonomopoulos S, Ragoussis I, Barry T, van der Helm E, Jolic D, Richardson H, Jansen H, Tyson JR, Jain M, Brown BL. Reddington K, et al. Among authors: van der helm e. Gigascience. 2020 Jun 1;9(6):giaa053. doi: 10.1093/gigascience/giaa053. Gigascience. 2020. PMID: 32520351 Free PMC article.
Antibiotic Treatment Drives the Diversification of the Human Gut Resistome.
Li J, Rettedal EA, van der Helm E, Ellabaan M, Panagiotou G, Sommer MOA. Li J, et al. Among authors: van der helm e. Genomics Proteomics Bioinformatics. 2019 Feb;17(1):39-51. doi: 10.1016/j.gpb.2018.12.003. Epub 2019 Apr 23. Genomics Proteomics Bioinformatics. 2019. PMID: 31026582 Free PMC article.
29 results