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A class of anti-inflammatory lipids decrease with aging in the central nervous system.
Nat Chem Biol. 2023 Feb;19(2):187-197. doi: 10.1038/s41589-022-01165-6. Epub 2022 Oct 20.
Nat Chem Biol. 2023.
PMID: 36266352
Free PMC article.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, Saghatelian A.
Erikci Ertunc M, et al.
J Biol Chem. 2020 May 1;295(18):5891-5905. doi: 10.1074/jbc.RA119.012145. Epub 2020 Mar 9.
J Biol Chem. 2020.
PMID: 32152231
Free PMC article.
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