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A class of anti-inflammatory lipids decrease with aging in the central nervous system.
Tan D, Konduri S, Erikci Ertunc M, Zhang P, Wang J, Chang T, Pinto AFM, Rocha A, Donaldson CJ, Vaughan JM, Ludwig RG, Willey E, Iyer M, Gray PC, Maher P, Allen NJ, Zuchero JB, Dillin A, Mori MA, Kohama SG, Siegel D, Saghatelian A. Tan D, et al. Nat Chem Biol. 2023 Feb;19(2):187-197. doi: 10.1038/s41589-022-01165-6. Epub 2022 Oct 20. Nat Chem Biol. 2023. PMID: 36266352 Free PMC article.
Accurate annotation of human protein-coding small open reading frames.
Martinez TF, Chu Q, Donaldson C, Tan D, Shokhirev MN, Saghatelian A. Martinez TF, et al. Among authors: tan d. Nat Chem Biol. 2020 Apr;16(4):458-468. doi: 10.1038/s41589-019-0425-0. Epub 2019 Dec 9. Nat Chem Biol. 2020. PMID: 31819274 Free PMC article.
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids.
Patel R, Santoro A, Hofer P, Tan D, Oberer M, Nelson AT, Konduri S, Siegel D, Zechner R, Saghatelian A, Kahn BB. Patel R, et al. Among authors: tan d. Nature. 2022 Jun;606(7916):968-975. doi: 10.1038/s41586-022-04787-x. Epub 2022 Jun 8. Nature. 2022. PMID: 35676490 Free PMC article.
Regulation of the ER stress response by a mitochondrial microprotein.
Chu Q, Martinez TF, Novak SW, Donaldson CJ, Tan D, Vaughan JM, Chang T, Diedrich JK, Andrade L, Kim A, Zhang T, Manor U, Saghatelian A. Chu Q, et al. Among authors: tan d. Nat Commun. 2019 Oct 25;10(1):4883. doi: 10.1038/s41467-019-12816-z. Nat Commun. 2019. PMID: 31653868 Free PMC article.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, Saghatelian A. Erikci Ertunc M, et al. Among authors: tan d. J Biol Chem. 2020 May 1;295(18):5891-5905. doi: 10.1074/jbc.RA119.012145. Epub 2020 Mar 9. J Biol Chem. 2020. PMID: 32152231 Free PMC article.
MIEF1 Microprotein Regulates Mitochondrial Translation.
Rathore A, Chu Q, Tan D, Martinez TF, Donaldson CJ, Diedrich JK, Yates JR 3rd, Saghatelian A. Rathore A, et al. Among authors: tan d. Biochemistry. 2018 Sep 25;57(38):5564-5575. doi: 10.1021/acs.biochem.8b00726. Epub 2018 Sep 14. Biochemistry. 2018. PMID: 30215512 Free PMC article.
CasX enzymes comprise a distinct family of RNA-guided genome editors.
Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brötzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA. Liu JJ, et al. Among authors: tan d. Nature. 2019 Feb;566(7743):218-223. doi: 10.1038/s41586-019-0908-x. Epub 2019 Feb 4. Nature. 2019. PMID: 30718774 Free PMC article.
Author Correction: CasX enzymes comprise a distinct family of RNA-guided genome editors.
Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brötzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA. Liu JJ, et al. Among authors: tan d. Nature. 2019 Apr;568(7752):E8-E10. doi: 10.1038/s41586-019-1084-8. Nature. 2019. PMID: 30944483
4,175 results