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A class of anti-inflammatory lipids decrease with aging in the central nervous system.
Tan D, Konduri S, Erikci Ertunc M, Zhang P, Wang J, Chang T, Pinto AFM, Rocha A, Donaldson CJ, Vaughan JM, Ludwig RG, Willey E, Iyer M, Gray PC, Maher P, Allen NJ, Zuchero JB, Dillin A, Mori MA, Kohama SG, Siegel D, Saghatelian A. Tan D, et al. Among authors: vaughan jm. Nat Chem Biol. 2023 Feb;19(2):187-197. doi: 10.1038/s41589-022-01165-6. Epub 2022 Oct 20. Nat Chem Biol. 2023. PMID: 36266352 Free PMC article.
HtrA1 Proteolysis of ApoE In Vitro Is Allele Selective.
Chu Q, Diedrich JK, Vaughan JM, Donaldson CJ, Nunn MF, Lee KF, Saghatelian A. Chu Q, et al. Among authors: vaughan jm. J Am Chem Soc. 2016 Aug 3;138(30):9473-8. doi: 10.1021/jacs.6b03463. Epub 2016 Jul 19. J Am Chem Soc. 2016. PMID: 27379525 Free PMC article.
Regulation of the ER stress response by a mitochondrial microprotein.
Chu Q, Martinez TF, Novak SW, Donaldson CJ, Tan D, Vaughan JM, Chang T, Diedrich JK, Andrade L, Kim A, Zhang T, Manor U, Saghatelian A. Chu Q, et al. Among authors: vaughan jm. Nat Commun. 2019 Oct 25;10(1):4883. doi: 10.1038/s41467-019-12816-z. Nat Commun. 2019. PMID: 31653868 Free PMC article.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, Saghatelian A. Erikci Ertunc M, et al. Among authors: vaughan jm. J Biol Chem. 2020 May 1;295(18):5891-5905. doi: 10.1074/jbc.RA119.012145. Epub 2020 Mar 9. J Biol Chem. 2020. PMID: 32152231 Free PMC article.
116 results