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Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Petzold T, Zhang Z, Ballesteros I, Saleh I, Polzin A, Thienel M, Liu L, Ul Ain Q, Ehreiser V, Weber C, Kilani B, Mertsch P, Götschke J, Cremer S, Fu W, Lorenz M, Ishikawa-Ankerhold H, Raatz E, El-Nemr S, Görlach A, Marhuenda E, Stark K, Pircher J, Stegner D, Gieger C, Schmidt-Supprian M, Gaertner F, Almendros I, Kelm M, Schulz C, Hidalgo A, Massberg S. Petzold T, et al. Among authors: pircher j. Immunity. 2022 Dec 13;55(12):2285-2299.e7. doi: 10.1016/j.immuni.2022.10.001. Epub 2022 Oct 21. Immunity. 2022. PMID: 36272416 Free PMC article.
Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.
Novotny J, Chandraratne S, Weinberger T, Philippi V, Stark K, Ehrlich A, Pircher J, Konrad I, Oberdieck P, Titova A, Hoti Q, Schubert I, Legate KR, Urtz N, Lorenz M, Pelisek J, Massberg S, von Brühl ML, Schulz C. Novotny J, et al. Among authors: pircher j. PLoS One. 2018 Jan 2;13(1):e0190728. doi: 10.1371/journal.pone.0190728. eCollection 2018. PLoS One. 2018. PMID: 29293656 Free PMC article.
Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation.
Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C. Pircher J, et al. Nat Commun. 2018 Apr 18;9(1):1523. doi: 10.1038/s41467-018-03925-2. Nat Commun. 2018. PMID: 29670076 Free PMC article.
Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.
Weckbach LT, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, Pick R, Salvermoser M, Czermak T, Pircher J, Sorrelle N, Migliorini M, Strickland DK, Klingel K, Brinkmann V, Abu Abed U, Eriksson U, Massberg S, Brunner S, Walzog B. Weckbach LT, et al. Among authors: pircher j. J Exp Med. 2019 Feb 4;216(2):350-368. doi: 10.1084/jem.20181102. Epub 2019 Jan 15. J Exp Med. 2019. PMID: 30647120 Free PMC article.
Role of RXRβ in platelet function and arterial thrombosis.
Lüsebrink E, Warm V, Pircher J, Ehrlich A, Zhang Z, Strecker J, Chambon P, Massberg S, Schulz C, Petzold T. Lüsebrink E, et al. Among authors: pircher j. J Thromb Haemost. 2019 Sep;17(9):1489-1499. doi: 10.1111/jth.14531. Epub 2019 Jul 1. J Thromb Haemost. 2019. PMID: 31172692 Free article.
Platelet-Neutrophil Crosstalk in Atherothrombosis.
Pircher J, Engelmann B, Massberg S, Schulz C. Pircher J, et al. Thromb Haemost. 2019 Aug;119(8):1274-1282. doi: 10.1055/s-0039-1692983. Epub 2019 Jun 29. Thromb Haemost. 2019. PMID: 31254975 Review.
55 results