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Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.
Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P; Psychiatric Genomics Consortium (PGC); Bipolar Disorder and Schizophrenia Working Groups; Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM. Andreassen OA, et al. Among authors: thompson wk. PLoS Genet. 2013 Apr;9(4):e1003455. doi: 10.1371/journal.pgen.1003455. Epub 2013 Apr 25. PLoS Genet. 2013. PMID: 23637625 Free PMC article.
Genetic Markers of Human Evolution Are Enriched in Schizophrenia.
Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, Thompson WK, Zuber V; Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium; Winsvold BS, Zwart JA, Collier DA, Desikan RS, Melle I, Werge T, Dale AM, Djurovic S, Andreassen OA. Srinivasan S, et al. Among authors: thompson wk. Biol Psychiatry. 2016 Aug 15;80(4):284-292. doi: 10.1016/j.biopsych.2015.10.009. Epub 2015 Oct 21. Biol Psychiatry. 2016. PMID: 26681495 Free PMC article.
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS.
Wang Y, Thompson WK, Schork AJ, Holland D, Chen CH, Bettella F, Desikan RS, Li W, Witoelar A, Zuber V, Devor A; Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium; Enhancing Neuro Imaging Genetics through Meta Analysis Consortium; Nöthen MM, Rietschel M, Chen Q, Werge T, Cichon S, Weinberger DR, Djurovic S, O'Donovan M, Visscher PM, Andreassen OA, Dale AM. Wang Y, et al. Among authors: thompson wk. PLoS Genet. 2016 Jan 25;12(1):e1005803. doi: 10.1371/journal.pgen.1005803. eCollection 2016 Jan. PLoS Genet. 2016. PMID: 26808560 Free PMC article.
Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics.
Holland D, Wang Y, Thompson WK, Schork A, Chen CH, Lo MT, Witoelar A; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Enhancing Neuro Imaging Genetics through Meta Analysis Consortium; Werge T, O'Donovan M, Andreassen OA, Dale AM. Holland D, et al. Among authors: thompson wk. Front Genet. 2016 Feb 16;7:15. doi: 10.3389/fgene.2016.00015. eCollection 2016. Front Genet. 2016. PMID: 26909100 Free PMC article.
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.
Sapkota Y, Steinthorsdottir V, Morris AP, Fassbender A, Rahmioglu N, De Vivo I, Buring JE, Zhang F, Edwards TL, Jones S, O D, Peterse D, Rexrode KM, Ridker PM, Schork AJ, MacGregor S, Martin NG, Becker CM, Adachi S, Yoshihara K, Enomoto T, Takahashi A, Kamatani Y, Matsuda K, Kubo M, Thorleifsson G, Geirsson RT, Thorsteinsdottir U, Wallace LM; iPSYCH-SSI-Broad Group; Yang J, Velez Edwards DR, Nyegaard M, Low SK, Zondervan KT, Missmer SA, D'Hooghe T, Montgomery GW, Chasman DI, Stefansson K, Tung JY, Nyholt DR. Sapkota Y, et al. Nat Commun. 2017 May 24;8:15539. doi: 10.1038/ncomms15539. Nat Commun. 2017. PMID: 28537267 Free PMC article.
Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum.
Ganna A, Satterstrom FK, Zekavat SM, Das I, Kurki MI, Churchhouse C, Alfoldi J, Martin AR, Havulinna AS, Byrnes A, Thompson WK, Nielsen PR, Karczewski KJ, Saarentaus E, Rivas MA, Gupta N, Pietiläinen O, Emdin CA, Lescai F, Bybjerg-Grauholm J, Flannick J; GoT2D/T2D-GENES Consortium; Mercader JM, Udler M; SIGMA Consortium Helmsley IBD Exome Sequencing Project; FinMetSeq Consortium; iPSYCH-Broad Consortium; Laakso M, Salomaa V, Hultman C, Ripatti S, Hämäläinen E, Moilanen JS, Körkkö J, Kuismin O, Nordentoft M, Hougaard DM, Mors O, Werge T, Mortensen PB, MacArthur D, Daly MJ, Sullivan PF, Locke AE, Palotie A, Børglum AD, Kathiresan S, Neale BM. Ganna A, et al. Among authors: thompson wk. Am J Hum Genet. 2018 Jun 7;102(6):1204-1211. doi: 10.1016/j.ajhg.2018.05.002. Epub 2018 May 31. Am J Hum Genet. 2018. PMID: 29861106 Free PMC article.
Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study.
Olsen L, Sparsø T, Weinsheimer SM, Dos Santos MBQ, Mazin W, Rosengren A, Sanchez XC, Hoeffding LK, Schmock H, Baekvad-Hansen M, Bybjerg-Grauholm J, Daly MJ, Neale BM, Pedersen MG, Agerbo E, Mors O, Børglum A, Nordentoft M, Hougaard DM, Mortensen PB, Geschwind DH, Pedersen C, Thompson WK, Werge T. Olsen L, et al. Among authors: thompson wk. Lancet Psychiatry. 2018 Jul;5(7):573-580. doi: 10.1016/S2215-0366(18)30168-8. Epub 2018 Jun 7. Lancet Psychiatry. 2018. PMID: 29886042 Free PMC article.
Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study.
Erlangsen A, Appadurai V, Wang Y, Turecki G, Mors O, Werge T, Mortensen PB, Starnawska A, Børglum AD, Schork A, Nudel R, Bækvad-Hansen M, Bybjerg-Grauholm J, Hougaard DM, Thompson WK, Nordentoft M, Agerbo E. Erlangsen A, et al. Among authors: thompson wk. Mol Psychiatry. 2020 Oct;25(10):2410-2421. doi: 10.1038/s41380-018-0218-y. Epub 2018 Aug 16. Mol Psychiatry. 2020. PMID: 30116032 Free PMC article.
339 results