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A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking.
Higgins-Chen AT, Thrush KL, Wang Y, Minteer CJ, Kuo PL, Wang M, Niimi P, Sturm G, Lin J, Moore AZ, Bandinelli S, Vinkers CH, Vermetten E, Rutten BPF, Geuze E, Okhuijsen-Pfeifer C, van der Horst MZ, Schreiter S, Gutwinski S, Luykx JJ, Picard M, Ferrucci L, Crimmins EM, Boks MP, Hägg S, Hu-Seliger TT, Levine ME. Higgins-Chen AT, et al. Among authors: thrush kl. Nat Aging. 2022 Jul;2(7):644-661. doi: 10.1038/s43587-022-00248-2. Epub 2022 Jul 15. Nat Aging. 2022. PMID: 36277076 Free PMC article.
Underlying features of epigenetic aging clocks in vivo and in vitro.
Liu Z, Leung D, Thrush K, Zhao W, Ratliff S, Tanaka T, Schmitz LL, Smith JA, Ferrucci L, Levine ME. Liu Z, et al. Aging Cell. 2020 Oct;19(10):e13229. doi: 10.1111/acel.13229. Epub 2020 Sep 15. Aging Cell. 2020. PMID: 32930491 Free PMC article.
Aging biomarkers and the brain.
Higgins-Chen AT, Thrush KL, Levine ME. Higgins-Chen AT, et al. Among authors: thrush kl. Semin Cell Dev Biol. 2021 Aug;116:180-193. doi: 10.1016/j.semcdb.2021.01.003. Epub 2021 Jan 25. Semin Cell Dev Biol. 2021. PMID: 33509689 Free PMC article. Review.