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Multiomics study of nonalcoholic fatty liver disease.
Sveinbjornsson G, Ulfarsson MO, Thorolfsdottir RB, Jonsson BA, Einarsson E, Gunnlaugsson G, Rognvaldsson S, Arnar DO, Baldvinsson M, Bjarnason RG; DBDS Genomic consortium; Eiriksdottir T, Erikstrup C, Ferkingstad E, Halldorsson GH, Helgason H, Helgadottir A, Hindhede L, Hjorleifsson G, Jones D, Knowlton KU, Lund SH, Melsted P, Norland K, Olafsson I, Olafsson S, Oskarsson GR, Ostrowski SR, Pedersen OB, Snaebjarnarson AS, Sigurdsson E, Steinthorsdottir V, Schwinn M, Thorgeirsson G, Thorleifsson G, Jonsdottir I, Bundgaard H, Nadauld L, Bjornsson ES, Rulifson IC, Rafnar T, Norddahl GL, Thorsteinsdottir U, Sulem P, Gudbjartsson DF, Holm H, Stefansson K. Sveinbjornsson G, et al. Among authors: rulifson ic. Nat Genet. 2022 Nov;54(11):1652-1663. doi: 10.1038/s41588-022-01199-5. Epub 2022 Oct 24. Nat Genet. 2022. PMID: 36280732 Free PMC article.
The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics.
Sherman DJ, Liu L, Mamrosh JL, Xie J, Ferbas J, Lomenick B, Ladinsky MS, Verma R, Rulifson IC, Deshaies RJ. Sherman DJ, et al. Among authors: rulifson ic. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2318619121. doi: 10.1073/pnas.2318619121. Epub 2024 Apr 24. Proc Natl Acad Sci U S A. 2024. PMID: 38657050 Free PMC article.
Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease.
Murray JK, Long J, Liu L, Singh S, Pruitt D, Ollmann M, Swearingen E, Hardy M, Homann O, Wu B, Holder JR, Sham K, Herberich B, Lo MC, Dou H, Shkumatov A, Florio M, Rulifson IC. Murray JK, et al. Among authors: rulifson ic. Nucleic Acid Ther. 2021 Oct;31(5):324-340. doi: 10.1089/nat.2021.0026. Epub 2021 Jul 23. Nucleic Acid Ther. 2021. PMID: 34297902
Identification of Human Islet Amyloid Polypeptide as a BACE2 Substrate.
Rulifson IC, Cao P, Miao L, Kopecky D, Huang L, White RD, Samayoa K, Gardner J, Wu X, Chen K, Tsuruda T, Homann O, Baribault H, Yamane H, Carlson T, Wiltzius J, Li Y. Rulifson IC, et al. PLoS One. 2016 Feb 3;11(2):e0147254. doi: 10.1371/journal.pone.0147254. eCollection 2016. PLoS One. 2016. PMID: 26840340 Free PMC article.
Inhibition of secreted frizzled-related protein 5 improves glucose metabolism.
Rulifson IC, Majeti JZ, Xiong Y, Hamburger A, Lee KJ, Miao L, Lu M, Gardner J, Gong Y, Wu H, Case R, Yeh WC, Richards WG, Baribault H, Li Y. Rulifson IC, et al. Am J Physiol Endocrinol Metab. 2014 Dec 15;307(12):E1144-52. doi: 10.1152/ajpendo.00283.2014. Epub 2014 Nov 4. Am J Physiol Endocrinol Metab. 2014. PMID: 25370851 Free article.
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