Hummel AM - Search Results

1

Autoreactive Plasmablasts After B Cell Depletion With Rituximab and Relapses in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Berti A, Hillion S, Konig MF, Moura MC, Hummel AM, Carmona E, Peikert T, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, Brunetta P, St Clair EW, Harris KM, Stone JH, Grandi G, Pers JO, Specks U, Cornec D. Berti A, et al. Among authors: hummel am. Arthritis Rheumatol. 2023 May;75(5):736-747. doi: 10.1002/art.42388. Epub 2023 Mar 15. Arthritis Rheumatol. 2023. PMID: 36281741 Free PMC article.

2

Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA.

Specks U, Fass DN, Fautsch MP, Hummel AM, Viss MA. Specks U, et al. Among authors: hummel am. FEBS Lett. 1996 Jul 29;390(3):265-70. doi: 10.1016/0014-5793(96)00669-2. FEBS Lett. 1996. PMID: 8706874 Free article.

3

A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide.

Sun J, Fass DN, Viss MA, Hummel AM, Tang H, Homburger HA, Specks U. Sun J, et al. Among authors: hummel am. Clin Exp Immunol. 1998 Nov;114(2):320-6. doi: 10.1046/j.1365-2249.1998.00730.x. Clin Exp Immunol. 1998. PMID: 9822293 Free PMC article.

4

Effects of carboxy-terminal modifications of proteinase 3 (PR3) on the recognition by PR3-ANCA.

Capizzi SA, Viss MA, Hummel AM, Fass DN, Specks U. Capizzi SA, et al. Among authors: hummel am. Kidney Int. 2003 Feb;63(2):756-60. doi: 10.1046/j.1523-1755.2003.00765.x. Kidney Int. 2003. PMID: 12631144 Free article.

5

Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments.

Wiesner O, Litwiller RD, Hummel AM, Viss MA, McDonald CJ, Jenne DE, Fass DN, Specks U. Wiesner O, et al. Among authors: hummel am. FEBS Lett. 2005 Oct 10;579(24):5305-12. doi: 10.1016/j.febslet.2005.08.056. FEBS Lett. 2005. PMID: 16182289 Free article.

6

A novel capture-ELISA for detection of anti-neutrophil cytoplasmic antibodies (ANCA) based on c-myc peptide recognition in carboxy-terminally tagged recombinant neutrophil serine proteases.

Lee AS, Finkielman JD, Peikert T, Hummel AM, Viss MA, Specks U. Lee AS, et al. Among authors: hummel am. J Immunol Methods. 2005 Dec 20;307(1-2):62-72. doi: 10.1016/j.jim.2005.09.004. Epub 2005 Oct 3. J Immunol Methods. 2005. PMID: 16242707

7

Agreement of anti-neutrophil cytoplasmic antibody measurements obtained from serum and plasma.

Lee AS, Finkielman JD, Peikert T, Hummel AM, Viss MA, Jacob GL, Homburger HA, Specks U; Wegener's Granulomatosis Etanercept Trial Research Group. Lee AS, et al. Among authors: hummel am. Clin Exp Immunol. 2006 Oct;146(1):15-20. doi: 10.1111/j.1365-2249.2006.03179.x. Clin Exp Immunol. 2006. PMID: 16968393 Free PMC article.

8

Functional significance of Asn-linked glycosylation of proteinase 3 for enzymatic activity, processing, targeting, and recognition by anti-neutrophil cytoplasmic antibodies.

Specks U, Fass DN, Finkielman JD, Hummel AM, Viss MA, Litwiller RD, McDonald CJ. Specks U, et al. Among authors: hummel am. J Biochem. 2007 Jan;141(1):101-12. doi: 10.1093/jb/mvm008. Epub 2006 Dec 11. J Biochem. 2007. PMID: 17158864

9

ANCA are detectable in nearly all patients with active severe Wegener's granulomatosis.

Finkielman JD, Lee AS, Hummel AM, Viss MA, Jacob GL, Homburger HA, Peikert T, Hoffman GS, Merkel PA, Spiera R, St Clair EW, Davis JC Jr, McCune WJ, Tibbs AK, Ytterberg SR, Stone JH, Specks U; WGET Research Group. Finkielman JD, et al. Among authors: hummel am. Am J Med. 2007 Jul;120(7):643.e9-14. doi: 10.1016/j.amjmed.2006.08.016. Am J Med. 2007. PMID: 17602941

10

Antiproteinase 3 antineutrophil cytoplasmic antibodies and disease activity in Wegener granulomatosis.

Finkielman JD, Merkel PA, Schroeder D, Hoffman GS, Spiera R, St Clair EW, Davis JC Jr, McCune WJ, Lears AK, Ytterberg SR, Hummel AM, Viss MA, Peikert T, Stone JH, Specks U; WGET Research Group. Finkielman JD, et al. Among authors: hummel am. Ann Intern Med. 2007 Nov 6;147(9):611-9. doi: 10.7326/0003-4819-147-9-200711060-00005. Ann Intern Med. 2007. PMID: 17975183 Clinical Trial.

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