MacDonald PE - Search Results

1

Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding.

Alghamdi TA, Krentz NAJ, Smith N, Spigelman AF, Rajesh V, Jha A, Ferdaoussi M, Suzuki K, Yang J, Manning Fox JE, Sun H, Sun Z, Gloyn AL, MacDonald PE. Alghamdi TA, et al. Among authors: macdonald pe. Mol Metab. 2022 Dec;66:101621. doi: 10.1016/j.molmet.2022.101621. Epub 2022 Oct 26. Mol Metab. 2022. PMID: 36307047 Free PMC article.

2

Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells.

Pigeau GM, Kolic J, Ball BJ, Hoppa MB, Wang YW, Rückle T, Woo M, Manning Fox JE, MacDonald PE. Pigeau GM, et al. Among authors: macdonald pe. Diabetes. 2009 Sep;58(9):2084-92. doi: 10.2337/db08-1371. Epub 2009 Jun 23. Diabetes. 2009. PMID: 19549714 Free PMC article.

3

Voltage-dependent K(+) channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans.

Spigelman AF, Dai X, MacDonald PE. Spigelman AF, et al. Among authors: macdonald pe. Diabetologia. 2010 Sep;53(9):1917-26. doi: 10.1007/s00125-010-1759-z. Epub 2010 May 6. Diabetologia. 2010. PMID: 20446079

4

SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.

Dai XQ, Plummer G, Casimir M, Kang Y, Hajmrle C, Gaisano HY, Manning Fox JE, MacDonald PE. Dai XQ, et al. Among authors: macdonald pe. Diabetes. 2011 Mar;60(3):838-47. doi: 10.2337/db10-0440. Epub 2011 Jan 24. Diabetes. 2011. PMID: 21266332 Free PMC article.

5

The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.

Dai XQ, Manning Fox JE, Chikvashvili D, Casimir M, Plummer G, Hajmrle C, Spigelman AF, Kin T, Singer-Lahat D, Kang Y, Shapiro AM, Gaisano HY, Lotan I, Macdonald PE. Dai XQ, et al. Among authors: macdonald pe. Diabetologia. 2012 Jun;55(6):1709-20. doi: 10.1007/s00125-012-2512-6. Epub 2012 Mar 13. Diabetologia. 2012. PMID: 22411134

6

Novel roles of SUMO in pancreatic β-cells: thinking outside the nucleus.

Manning Fox JE, Hajmrle C, Macdonald PE. Manning Fox JE, et al. Among authors: macdonald pe. Can J Physiol Pharmacol. 2012 Jun;90(6):765-70. doi: 10.1139/y11-134. Epub 2012 Apr 9. Can J Physiol Pharmacol. 2012. PMID: 22486776 Review.

7

In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking.

Cai EP, Casimir M, Schroer SA, Luk CT, Shi SY, Choi D, Dai XQ, Hajmrle C, Spigelman AF, Zhu D, Gaisano HY, MacDonald PE, Woo M. Cai EP, et al. Among authors: macdonald pe. Diabetes. 2012 Jul;61(7):1708-18. doi: 10.2337/db11-1344. Epub 2012 Apr 12. Diabetes. 2012. PMID: 22498697 Free PMC article.

8

G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1.

Ferdaoussi M, Bergeron V, Zarrouki B, Kolic J, Cantley J, Fielitz J, Olson EN, Prentki M, Biden T, MacDonald PE, Poitout V. Ferdaoussi M, et al. Among authors: macdonald pe. Diabetologia. 2012 Oct;55(10):2682-2692. doi: 10.1007/s00125-012-2650-x. Epub 2012 Jul 22. Diabetologia. 2012. PMID: 22820510 Free PMC article.

9

SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells.

Kailey B, van de Bunt M, Cheley S, Johnson PR, MacDonald PE, Gloyn AL, Rorsman P, Braun M. Kailey B, et al. Among authors: macdonald pe. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. doi: 10.1152/ajpendo.00207.2012. Epub 2012 Aug 28. Am J Physiol Endocrinol Metab. 2012. PMID: 22932785 Free PMC article.

10

Functional plasticity of the human infant β-cell exocytotic phenotype.

Fox JE, Seeberger K, Dai XQ, Lyon J, Spigelman AF, Kolic J, Hajmrle C, Joseph JW, Kin T, Shapiro AM, Korbutt G, MacDonald PE. Fox JE, et al. Among authors: macdonald pe. Endocrinology. 2013 Apr;154(4):1392-9. doi: 10.1210/en.2012-1934. Epub 2013 Feb 28. Endocrinology. 2013. PMID: 23449893

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