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Decreased Water Mobility Contributes To Increased α-Synuclein Aggregation.
Stephens AD, Kölbel J, Moons R, Chung CW, Ruggiero MT, Mahmoudi N, Shmool TA, McCoy TM, Nietlispach D, Routh AF, Sobott F, Zeitler JA, Kaminski Schierle GS. Stephens AD, et al. Among authors: kaminski schierle gs. Angew Chem Int Ed Engl. 2023 Feb 6;62(7):e202212063. doi: 10.1002/anie.202212063. Epub 2023 Jan 12. Angew Chem Int Ed Engl. 2023. PMID: 36316279 Free PMC article.
Feasibility of Coacervate-Like Nanostructure for Instant Drug Nanoformulation.
Zhu GH, Azharuddin M, Pramanik B, Roberg K, Biswas SK, D'arcy P, Lu M, Kaur A, Chen A, Dhara AK, Chivu A, Zhuang Y, Baker A, Liu X, Fairen-Jimenez D, Mazumder B, Chen R, Kaminski CF, Kaminski Schierle GS, Hinkula J, Slater NKH, Patra HK. Zhu GH, et al. Among authors: kaminski schierle gs. ACS Appl Mater Interfaces. 2023 Apr 12;15(14):17485-17494. doi: 10.1021/acsami.2c21586. Epub 2023 Mar 28. ACS Appl Mater Interfaces. 2023. PMID: 36976817 Free PMC article.
Structural basis of synaptic vesicle assembly promoted by α-synuclein.
Fusco G, Pape T, Stephens AD, Mahou P, Costa AR, Kaminski CF, Kaminski Schierle GS, Vendruscolo M, Veglia G, Dobson CM, De Simone A. Fusco G, et al. Among authors: kaminski schierle gs, kaminski cf. Nat Commun. 2016 Sep 19;7:12563. doi: 10.1038/ncomms12563. Nat Commun. 2016. PMID: 27640673 Free PMC article.
The Cellular Environment Affects Monomeric α-Synuclein Structure.
Stephens AD, Zacharopoulou M, Kaminski Schierle GS. Stephens AD, et al. Among authors: kaminski schierle gs. Trends Biochem Sci. 2019 May;44(5):453-466. doi: 10.1016/j.tibs.2018.11.005. Epub 2018 Dec 7. Trends Biochem Sci. 2019. PMID: 30527975 Review.
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans.
Huang C, Wagner-Valladolid S, Stephens AD, Jung R, Poudel C, Sinnige T, Lechler MC, Schlörit N, Lu M, Laine RF, Michel CH, Vendruscolo M, Kaminski CF, Kaminski Schierle GS, David DC. Huang C, et al. Among authors: kaminski schierle gs, kaminski cf. Elife. 2019 May 3;8:e43059. doi: 10.7554/eLife.43059. Elife. 2019. PMID: 31050339 Free PMC article.
Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans.
Laine RF, Sinnige T, Ma KY, Haack AJ, Poudel C, Gaida P, Curry N, Perni M, Nollen EAA, Dobson CM, Vendruscolo M, Kaminski Schierle GS, Kaminski CF. Laine RF, et al. Among authors: kaminski schierle gs, kaminski cf. ACS Chem Biol. 2019 Jul 19;14(7):1628-1636. doi: 10.1021/acschembio.9b00354. Epub 2019 Jun 27. ACS Chem Biol. 2019. PMID: 31246415 Free PMC article.
The role of water in amyloid aggregation kinetics.
Stephens AD, Kaminski Schierle GS. Stephens AD, et al. Among authors: kaminski schierle gs. Curr Opin Struct Biol. 2019 Oct;58:115-123. doi: 10.1016/j.sbi.2019.06.001. Epub 2019 Jul 10. Curr Opin Struct Biol. 2019. PMID: 31299481 Review.
84 results