Lozano G - Search Results

1

Omics analyses of a somatic Trp53^R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling.

Yu X, Zhang Y, Xiong S, McDaniel JM, Sun C, Chau GP, Gencel-Augusto J, Chachad D, Morrissey RL, Rao X, Wang J, Lozano G. Yu X, et al. Among authors: lozano g. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2210618119. doi: 10.1073/pnas.2210618119. Epub 2022 Nov 2. Proc Natl Acad Sci U S A. 2022. PMID: 36322759 Free PMC article.

2

Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation.

Kapoor M, Lozano G. Kapoor M, et al. Among authors: lozano g. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2834-7. doi: 10.1073/pnas.95.6.2834. Proc Natl Acad Sci U S A. 1998. PMID: 9501176 Free PMC article.

3

High metastatic potential in mice inheriting a targeted p53 missense mutation.

Liu G, McDonnell TJ, Montes de Oca Luna R, Kapoor M, Mims B, El-Naggar AK, Lozano G. Liu G, et al. Among authors: lozano g. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4174-9. doi: 10.1073/pnas.97.8.4174. Proc Natl Acad Sci U S A. 2000. PMID: 10760284 Free PMC article.

4

Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.

Grier JD, Xiong S, Elizondo-Fraire AC, Parant JM, Lozano G. Grier JD, et al. Among authors: lozano g. Mol Cell Biol. 2006 Jan;26(1):192-8. doi: 10.1128/MCB.26.1.192-198.2006. Mol Cell Biol. 2006. PMID: 16354690 Free PMC article.

5

Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.

Xiong S, Van Pelt CS, Elizondo-Fraire AC, Liu G, Lozano G. Xiong S, et al. Among authors: lozano g. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3226-31. doi: 10.1073/pnas.0508500103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492743 Free PMC article.

6

p21 delays tumor onset by preservation of chromosomal stability.

Barboza JA, Liu G, Ju Z, El-Naggar AK, Lozano G. Barboza JA, et al. Among authors: lozano g. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19842-7. doi: 10.1073/pnas.0606343104. Epub 2006 Dec 14. Proc Natl Acad Sci U S A. 2006. PMID: 17170138 Free PMC article.

7

Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.

Xiong S, Van Pelt CS, Elizondo-Fraire AC, Fernandez-Garcia B, Lozano G. Xiong S, et al. Among authors: lozano g. Circulation. 2007 Jun 12;115(23):2925-30. doi: 10.1161/CIRCULATIONAHA.107.689901. Epub 2007 May 28. Circulation. 2007. PMID: 17533180

8

High levels of the p53 inhibitor MDM4 in head and neck squamous carcinomas.

Valentin-Vega YA, Barboza JA, Chau GP, El-Naggar AK, Lozano G. Valentin-Vega YA, et al. Among authors: lozano g. Hum Pathol. 2007 Oct;38(10):1553-62. doi: 10.1016/j.humpath.2007.03.005. Epub 2007 Jul 24. Hum Pathol. 2007. PMID: 17651783 Free PMC article.

9

The p53-Mdm2 network in progenitor cell expansion during mouse postnatal development.

Liu G, Terzian T, Xiong S, Van Pelt CS, Audiffred A, Box NF, Lozano G. Liu G, et al. Among authors: lozano g. J Pathol. 2007 Dec;213(4):360-8. doi: 10.1002/path.2238. J Pathol. 2007. PMID: 17893884

10

Mtbp haploinsufficiency in mice increases tumor metastasis.

Iwakuma T, Tochigi Y, Van Pelt CS, Caldwell LC, Terzian T, Parant JM, Chau GP, Koch JG, Eischen CM, Lozano G. Iwakuma T, et al. Among authors: lozano g. Oncogene. 2008 Mar 20;27(13):1813-20. doi: 10.1038/sj.onc.1210827. Epub 2007 Oct 1. Oncogene. 2008. PMID: 17906694

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