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Omics analyses of a somatic Trp53R245W/+ breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling.
Yu X, Zhang Y, Xiong S, McDaniel JM, Sun C, Chau GP, Gencel-Augusto J, Chachad D, Morrissey RL, Rao X, Wang J, Lozano G. Yu X, et al. Among authors: zhang y. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2210618119. doi: 10.1073/pnas.2210618119. Epub 2022 Nov 2. Proc Natl Acad Sci U S A. 2022. PMID: 36322759 Free PMC article.
Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.
Li Q, Zhang Y, El-Naggar AK, Xiong S, Yang P, Jackson JG, Chau G, Lozano G. Li Q, et al. Among authors: zhang y. Mol Cancer Res. 2014 Jun;12(6):901-11. doi: 10.1158/1541-7786.MCR-14-0089. Epub 2014 Mar 5. Mol Cancer Res. 2014. PMID: 24598047 Free PMC article.
Tissue-specific and age-dependent effects of global Mdm2 loss.
Zhang Y, Xiong S, Li Q, Hu S, Tashakori M, Van Pelt C, You MJ, Pageon L, Lozano G. Zhang Y, et al. J Pathol. 2014 Aug;233(4):380-91. doi: 10.1002/path.4368. Epub 2014 Jun 9. J Pathol. 2014. PMID: 24789767 Free PMC article.
Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.
Xiong S, Tu H, Kollareddy M, Pant V, Li Q, Zhang Y, Jackson JG, Suh YA, Elizondo-Fraire AC, Yang P, Chau G, Tashakori M, Wasylishen AR, Ju Z, Solomon H, Rotter V, Liu B, El-Naggar AK, Donehower LA, Martinez LA, Lozano G. Xiong S, et al. Among authors: zhang y. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11145-50. doi: 10.1073/pnas.1404139111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024203 Free PMC article.
241,428 results
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