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Improving Outcomes for Infants After Cardiopulmonary Bypass Surgery for Congenital Heart Disease: A Commentary on Recent Randomized Controlled Trials.
Schlapbach LJ, Gibbons KS, Butt W, Kannankeril PJ, Li JS, Hill KD; Nitric Oxide During Cardiopulmonary Bypass to Improve Recovery in Infants With Congenital Heart Defects Follow-Up (NITRIC) Study Group and the Steroids to Reduce Systemic Inflammation after Infant Heart Surgery (STRESS) Network Investigators. Schlapbach LJ, et al. Pediatr Crit Care Med. 2023 Nov 1;24(11):961-965. doi: 10.1097/PCC.0000000000003344. Epub 2023 Aug 21. Pediatr Crit Care Med. 2023. PMID: 37607086
Methylprednisolone for Heart Surgery in Infants - A Randomized, Controlled Trial.
Hill KD, Kannankeril PJ, Jacobs JP, Baldwin HS, Jacobs ML, O'Brien SM, Bichel DP, Graham EM, Blasiole B, Resheidat A, Husain AS, Kumar SR, Kirchner JL, Gallup DS, Turek JW, Bleiweis M, Mettler B, Benscoter A, Wald E, Karamlou T, Van Bergen AH, Overman D, Eghtesady P, Butts R, Kim JS, Scott JP, Anderson BR, Swartz MF, McConnell PI, Vener DF, Li JS; STRESS Network Investigators. Hill KD, et al. Among authors: bichel dp. N Engl J Med. 2022 Dec 8;387(23):2138-2149. doi: 10.1056/NEJMoa2212667. Epub 2022 Nov 6. N Engl J Med. 2022. PMID: 36342116 Free PMC article. Clinical Trial.
Overcoming underpowering: Trial simulations and a global rank end point to optimize clinical trials in children with heart disease.
Hill KD, Baldwin HS, Bichel DP, Ellis AM, Graham EM, Hornik CP, Jacobs JP, Jaquiss RDB, Jacobs ML, Kannankeril PJ, Li JS, Torok R, Turek JW, O'Brien SM. Hill KD, et al. Among authors: bichel dp. Am Heart J. 2020 Aug;226:188-197. doi: 10.1016/j.ahj.2020.05.011. Epub 2020 May 20. Am Heart J. 2020. PMID: 32599259 Free PMC article.
Rationale and design of the STeroids to REduce Systemic inflammation after infant heart Surgery (STRESS) trial.
Hill KD, Baldwin HS, Bichel DP, Butts RJ, Chamberlain RC, Ellis AM, Graham EM, Hickerson J, Hornik CP, Jacobs JP, Jacobs ML, Jaquiss RD, Kannankeril PJ, O'Brien SM, Torok R, Turek JW, Li JS; STRESS Network Investigators. Hill KD, et al. Among authors: bichel dp. Am Heart J. 2020 Feb;220:192-202. doi: 10.1016/j.ahj.2019.11.016. Epub 2019 Dec 9. Am Heart J. 2020. PMID: 31855716 Free PMC article. Clinical Trial.