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A large-scale genome-wide association study meta-analysis of cannabis use disorder.
Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, Sanchez-Roige S, Paul SE, Wendt FR, Clarke TK, Lai D, Reginsson GW, Zhou H, He J, Baranger DAA, Gudbjartsson DF, Wedow R, Adkins DE, Adkins AE, Alexander J, Bacanu SA, Bigdeli TB, Boden J, Brown SA, Bucholz KK, Bybjerg-Grauholm J, Corley RP, Degenhardt L, Dick DM, Domingue BW, Fox L, Goate AM, Gordon SD, Hack LM, Hancock DB, Hartz SM, Hickie IB, Hougaard DM, Krauter K, Lind PA, McClintick JN, McQueen MB, Meyers JL, Montgomery GW, Mors O, Mortensen PB, Nordentoft M, Pearson JF, Peterson RE, Reynolds MD, Rice JP, Runarsdottir V, Saccone NL, Sherva R, Silberg JL, Tarter RE, Tyrfingsson T, Wall TL, Webb BT, Werge T, Wetherill L, Wright MJ, Zellers S, Adams MJ, Bierut LJ, Boardman JD, Copeland WE, Farrer LA, Foroud TM, Gillespie NA, Grucza RA, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono WG, Johnson EO, Kendler KS, Kennedy MA, Kranzler HR, Madden PAF, Maes HH, Maher BS, Martin NG, McGue M, McIntosh AM, Medland SE, Nelson EC, Porjesz B, Riley BP, Stallings MC, Vanyukov MM, Vrieze S; Psychiatric Genomics Consortium Substance Use Disorders Workgroup; Davis LK, Bogdan R, Geler… See abstract for full author list ➔ Johnson EC, et al. Among authors: hatoum as. Lancet Psychiatry. 2020 Dec;7(12):1032-1045. doi: 10.1016/S2215-0366(20)30339-4. Epub 2020 Oct 20. Lancet Psychiatry. 2020. PMID: 33096046 Free PMC article.
Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder.
Johnson EC, Kapoor M, Hatoum AS, Zhou H, Polimanti R, Wendt FR, Walters RK, Lai D, Kember RL, Hartz S, Meyers JL, Peterson RE, Ripke S, Bigdeli TB, Fanous AH, Pato CN, Pato MT, Goate AM, Kranzler HR, O'Donovan MC, Walters JTR, Gelernter J, Edenberg HJ, Agrawal A. Johnson EC, et al. Among authors: hatoum as. Psychol Med. 2023 Mar;53(4):1196-1204. doi: 10.1017/S003329172100266X. Epub 2021 Jul 7. Psychol Med. 2023. PMID: 34231451 Free PMC article.
Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.
Deak JD, Zhou H, Galimberti M, Levey DF, Wendt FR, Sanchez-Roige S, Hatoum AS, Johnson EC, Nunez YZ, Demontis D, Børglum AD, Rajagopal VM, Jennings MV, Kember RL, Justice AC, Edenberg HJ, Agrawal A, Polimanti R, Kranzler HR, Gelernter J. Deak JD, et al. Among authors: hatoum as. Mol Psychiatry. 2022 Oct;27(10):3970-3979. doi: 10.1038/s41380-022-01709-1. Epub 2022 Jul 25. Mol Psychiatry. 2022. PMID: 35879402 Free PMC article.
Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.
Hatoum AS, Morrison CL, Mitchell EC, Lam M, Benca-Bachman CE, Reineberg AE, Palmer RHC, Evans LM, Keller MC, Friedman NP. Hatoum AS, et al. Biol Psychiatry. 2023 Jan 1;93(1):59-70. doi: 10.1016/j.biopsych.2022.06.034. Epub 2022 Jul 14. Biol Psychiatry. 2023. PMID: 36150907 Free PMC article.
Multi-ancestry study of the genetics of problematic alcohol use in >1 million individuals.
Zhou H, Kember RL, Deak JD, Xu H, Toikumo S, Yuan K, Lind PA, Farajzadeh L, Wang L, Hatoum AS, Johnson J, Lee H, Mallard TT, Xu J, Johnston KJA, Johnson EC, Galimberti M, Dao C, Levey DF, Overstreet C, Byrne EM, Gillespie NA, Gordon S, Hickie IB, Whitfield JB, Xu K, Zhao H, Huckins LM, Davis LK, Sanchez-Roige S, Madden PAF, Heath AC, Medland SE, Martin NG, Ge T, Smoller JW, Hougaard DM, Børglum AD, Demontis D, Krystal JH, Gaziano JM, Edenberg HJ, Agrawal A; Million Veteran Program; Justice AC, Stein MB, Kranzler HR, Gelernter J. Zhou H, et al. Among authors: hatoum as. medRxiv [Preprint]. 2023 Jan 30:2023.01.24.23284960. doi: 10.1101/2023.01.24.23284960. medRxiv. 2023. PMID: 36747741 Free PMC article. Updated. Preprint.
Multi-omics cannot replace sample size in genome-wide association studies.
Baranger DAA, Hatoum AS, Polimanti R, Gelernter J, Edenberg HJ, Bogdan R, Agrawal A. Baranger DAA, et al. Among authors: hatoum as. Genes Brain Behav. 2023 Dec;22(6):e12846. doi: 10.1111/gbb.12846. Epub 2023 Mar 28. Genes Brain Behav. 2023. PMID: 36977197 Free PMC article.
63 results