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A public resource of baseline data from the Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial.
Reiman EM, Pruzin JJ, Rios-Romenets S, Brown C, Giraldo M, Acosta-Baena N, Tobon C, Hu N, Chen Y, Ghisays V, Enos J, Goradia DD, Lee W, Luo J, Malek-Ahmadi M, Protas H, Thomas RG, Chen K, Su Y, Boker C, Mastroeni D, Alvarez S, Quiroz YT, Langbaum JB, Sink KM, Lopera F, Tariot PN; API ADAD Colombia Trial Group. Reiman EM, et al. Among authors: pruzin jj. Alzheimers Dement. 2023 May;19(5):1938-1946. doi: 10.1002/alz.12843. Epub 2022 Nov 14. Alzheimers Dement. 2023. PMID: 36373344 Free PMC article.
Memory complaints, dementia, and neuropathology in older blacks and whites.
Arvanitakis Z, Leurgans SE, Fleischman DA, Schneider JA, Rajan KB, Pruzin JJ, Shah RC, Evans DA, Barnes LL, Bennett DA. Arvanitakis Z, et al. Among authors: pruzin jj. Ann Neurol. 2018 Apr;83(4):718-729. doi: 10.1002/ana.25189. Epub 2018 Mar 30. Ann Neurol. 2018. PMID: 29466839 Free PMC article.
Hypometabolism in Alzheimer-affected brain regions in cognitively healthy Latino individuals carrying the apolipoprotein E epsilon4 allele.
Langbaum JB, Chen K, Caselli RJ, Lee W, Reschke C, Bandy D, Alexander GE, Burns CM, Kaszniak AW, Reeder SA, Corneveaux JJ, Allen AN, Pruzin J, Huentelman MJ, Fleisher AS, Reiman EM. Langbaum JB, et al. Among authors: pruzin j. Arch Neurol. 2010 Apr;67(4):462-8. doi: 10.1001/archneurol.2010.30. Arch Neurol. 2010. PMID: 20385913 Free PMC article.
Association between GAB2 haplotype and higher glucose metabolism in Alzheimer's disease-affected brain regions in cognitively normal APOEε4 carriers.
Liang WS, Chen K, Lee W, Sidhar K, Corneveaux JJ, Allen AN, Myers A, Villa S, Meechoovet B, Pruzin J, Bandy D, Fleisher AS, Langbaum JB, Huentelman MJ, Jensen K, Dunckley T, Caselli RJ, Kaib S, Reiman EM. Liang WS, et al. Among authors: pruzin j. Neuroimage. 2011 Feb 1;54(3):1896-902. doi: 10.1016/j.neuroimage.2010.09.066. Epub 2010 Oct 1. Neuroimage. 2011. PMID: 20888920 Free PMC article.
Plasma IL-12/IFN-γ axis predicts cognitive trajectories in cognitively unimpaired older adults.
Yang HS, Zhang C, Carlyle BC, Zhen SY, Trombetta BA, Schultz AP, Pruzin JJ, Fitzpatrick CD, Yau WW, Kirn DR, Rentz DM, Arnold SE, Johnson KA, Sperling RA, Chhatwal JP, Tanzi RE. Yang HS, et al. Among authors: pruzin jj. Alzheimers Dement. 2022 Apr;18(4):645-653. doi: 10.1002/alz.12399. Epub 2021 Jun 23. Alzheimers Dement. 2022. PMID: 34160128 Free PMC article.
Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer's disease.
Langella S, Barksdale NG, Vasquez D, Aguillon D, Chen Y, Su Y, Acosta-Baena N, Acosta-Uribe J, Baena AY, Garcia-Ospina G, Giraldo-Chica M, Tirado V, Muñoz C, Ríos-Romenets S, Guzman-Martínez C, Oliveira G, Yang HS, Vila-Castelar C, Pruzin JJ, Ghisays V, Arboleda-Velasquez JF, Kosik KS, Reiman EM, Lopera F, Quiroz YT. Langella S, et al. Among authors: pruzin jj. Nat Commun. 2023 Aug 23;14(1):5120. doi: 10.1038/s41467-023-40775-z. Nat Commun. 2023. PMID: 37612284 Free PMC article.
Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.
Bateman RJ, Smith J, Donohue MC, Delmar P, Abbas R, Salloway S, Wojtowicz J, Blennow K, Bittner T, Black SE, Klein G, Boada M, Grimmer T, Tamaoka A, Perry RJ, Turner RS, Watson D, Woodward M, Thanasopoulou A, Lane C, Baudler M, Fox NC, Cummings JL, Fontoura P, Doody RS; GRADUATE I and II Investigators and the Gantenerumab Study Group. Bateman RJ, et al. N Engl J Med. 2023 Nov 16;389(20):1862-1876. doi: 10.1056/NEJMoa2304430. N Engl J Med. 2023. PMID: 37966285 Clinical Trial.
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, Nalls MA, Chen K, Lee W, Chewning K, Villa SE, Meechoovet HB, Gerber JD, Frost D, Benson HL, O'Reilly S, Chibnik LB, Shulman JM, Singleton AB, Craig DW, Van Keuren-Jensen KR, Dunckley T, Bennett DA, De Jager PL, Heward C, Hardy J, Reiman EM, Huentelman MJ. Corneveaux JJ, et al. Among authors: pruzin jj. Hum Mol Genet. 2010 Aug 15;19(16):3295-301. doi: 10.1093/hmg/ddq221. Epub 2010 Jun 9. Hum Mol Genet. 2010. PMID: 20534741 Free PMC article.
Associations of Physical Activity and β-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults.
Rabin JS, Klein H, Kirn DR, Schultz AP, Yang HS, Hampton O, Jiang S, Buckley RF, Viswanathan A, Hedden T, Pruzin J, Yau WW, Guzmán-Vélez E, Quiroz YT, Properzi M, Marshall GA, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Rabin JS, et al. JAMA Neurol. 2019 Oct 1;76(10):1203-1210. doi: 10.1001/jamaneurol.2019.1879. JAMA Neurol. 2019. PMID: 31312836 Free PMC article.
Physical activity is associated with increased resting-state functional connectivity in networks predictive of cognitive decline in clinically unimpaired older adults.
Pruzin JJ, Klein H, Rabin JS, Schultz AP, Kirn DR, Yang HS, Buckley RF, Scott MR, Properzi M, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Pruzin JJ, et al. Alzheimers Dement (Amst). 2022 Jul 7;14(1):e12319. doi: 10.1002/dad2.12319. eCollection 2022. Alzheimers Dement (Amst). 2022. PMID: 35821672 Free PMC article.
23 results