Holtzman DM - Search Results

1

APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression.

Dincer A, Chen CD, McKay NS, Koenig LN, McCullough A, Flores S, Keefe SJ, Schultz SA, Feldman RL, Joseph-Mathurin N, Hornbeck RC, Cruchaga C, Schindler SE, Holtzman DM, Morris JC, Fagan AM, Benzinger TLS, Gordon BA. Dincer A, et al. Among authors: holtzman dm. Sci Transl Med. 2022 Nov 16;14(671):eabl7646. doi: 10.1126/scitranslmed.abl7646. Epub 2022 Nov 16. Sci Transl Med. 2022. PMID: 36383681 Free PMC article.

2

Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein.

Fagan AM, Bu G, Sun Y, Daugherty A, Holtzman DM. Fagan AM, et al. Among authors: holtzman dm. J Biol Chem. 1996 Nov 22;271(47):30121-5. doi: 10.1074/jbc.271.47.30121. J Biol Chem. 1996. PMID: 8939961 Free article.

3

High density lipoprotein decreases beta-amyloid toxicity in cortical cell culture.

Farhangrazi ZS, Ying H, Bu G, Dugan LL, Fagan AM, Choi DW, Holtzman DM. Farhangrazi ZS, et al. Among authors: holtzman dm. Neuroreport. 1997 Mar 24;8(5):1127-30. doi: 10.1097/00001756-199703240-00013. Neuroreport. 1997. PMID: 9175098

4

A role for TrkA during maturation of striatal and basal forebrain cholinergic neurons in vivo.

Fagan AM, Garber M, Barbacid M, Silos-Santiago I, Holtzman DM. Fagan AM, et al. Among authors: holtzman dm. J Neurosci. 1997 Oct 15;17(20):7644-54. doi: 10.1523/JNEUROSCI.17-20-07644.1997. J Neurosci. 1997. PMID: 9315886 Free PMC article.

5

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

Sun Y, Wu S, Bu G, Onifade MK, Patel SN, LaDu MJ, Fagan AM, Holtzman DM. Sun Y, et al. Among authors: holtzman dm. J Neurosci. 1998 May 1;18(9):3261-72. doi: 10.1523/JNEUROSCI.18-09-03261.1998. J Neurosci. 1998. PMID: 9547235 Free PMC article.

6

Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury.

Fagan AM, Murphy BA, Patel SN, Kilbridge JF, Mobley WC, Bu G, Holtzman DM. Fagan AM, et al. Among authors: holtzman dm. Exp Neurol. 1998 Jun;151(2):314-25. doi: 10.1006/exnr.1998.6818. Exp Neurol. 1998. PMID: 9628766

7

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease.

Holtzman DM, Bales KR, Wu S, Bhat P, Parsadanian M, Fagan AM, Chang LK, Sun Y, Paul SM. Holtzman DM, et al. J Clin Invest. 1999 Mar;103(6):R15-R21. doi: 10.1172/JCI6179. J Clin Invest. 1999. PMID: 10079115 Free PMC article.

8

Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice.

Fagan AM, Holtzman DM, Munson G, Mathur T, Schneider D, Chang LK, Getz GS, Reardon CA, Lukens J, Shah JA, LaDu MJ. Fagan AM, et al. Among authors: holtzman dm. J Biol Chem. 1999 Oct 15;274(42):30001-7. doi: 10.1074/jbc.274.42.30001. J Biol Chem. 1999. PMID: 10514484 Free article.

9

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease.

Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, Mackey B, Olney J, McKeel D, Wozniak D, Paul SM. Holtzman DM, et al. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2892-7. doi: 10.1073/pnas.050004797. Proc Natl Acad Sci U S A. 2000. PMID: 10694577 Free PMC article.

10

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT. Holtzman DM, et al. Ann Neurol. 2000 Jun;47(6):739-47. Ann Neurol. 2000. PMID: 10852539

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