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APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression.
Dincer A, Chen CD, McKay NS, Koenig LN, McCullough A, Flores S, Keefe SJ, Schultz SA, Feldman RL, Joseph-Mathurin N, Hornbeck RC, Cruchaga C, Schindler SE, Holtzman DM, Morris JC, Fagan AM, Benzinger TLS, Gordon BA. Dincer A, et al. Among authors: schindler se. Sci Transl Med. 2022 Nov 16;14(671):eabl7646. doi: 10.1126/scitranslmed.abl7646. Epub 2022 Nov 16. Sci Transl Med. 2022. PMID: 36383681 Free PMC article.
Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy.
Yanamandra K, Patel TK, Jiang H, Schindler S, Ulrich JD, Boxer AL, Miller BL, Kerwin DR, Gallardo G, Stewart F, Finn MB, Cairns NJ, Verghese PB, Fogelman I, West T, Braunstein J, Robinson G, Keyser J, Roh J, Knapik SS, Hu Y, Holtzman DM. Yanamandra K, et al. Sci Transl Med. 2017 Apr 19;9(386):eaal2029. doi: 10.1126/scitranslmed.aal2029. Sci Transl Med. 2017. PMID: 28424326 Free PMC article.
Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.
Del-Aguila JL, Fernández MV, Schindler S, Ibanez L, Deming Y, Ma S, Saef B, Black K, Budde J, Norton J, Chasse R; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Harari O, Goate A, Xiong C, Morris JC, Cruchaga C. Del-Aguila JL, et al. J Alzheimers Dis. 2018;62(2):745-756. doi: 10.3233/JAD-170834. J Alzheimers Dis. 2018. PMID: 29480181 Free PMC article.
Assessment of Racial Disparities in Biomarkers for Alzheimer Disease.
Morris JC, Schindler SE, McCue LM, Moulder KL, Benzinger TLS, Cruchaga C, Fagan AM, Grant E, Gordon BA, Holtzman DM, Xiong C. Morris JC, et al. Among authors: schindler se. JAMA Neurol. 2019 Mar 1;76(3):264-273. doi: 10.1001/jamaneurol.2018.4249. JAMA Neurol. 2019. PMID: 30615028 Free PMC article.
102 results