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Page 1
Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.
Frank KJ, Mulero-Sánchez A, Berninger A, Ruiz-Cañas L, Bosma A, Görgülü K, Wu N, Diakopoulos KN, Kaya-Aksoy E, Ruess DA, Kabacaoğlu D, Schmidt F, Kohlmann L, van Tellingen O, Thijssen B, van de Ven M, Proost N, Kossatz S, Weber WA, Sainz B Jr, Bernards R, Algül H, Lesina M, Mainardi S. Frank KJ, et al. Among authors: van de ven m, van tellingen o. Cell Rep Med. 2022 Nov 15;3(11):100815. doi: 10.1016/j.xcrm.2022.100815. Cell Rep Med. 2022. PMID: 36384095 Free PMC article.
An Experimenter's Guide to Glioblastoma Invasion Pathways.
de Gooijer MC, Guillén Navarro M, Bernards R, Wurdinger T, van Tellingen O. de Gooijer MC, et al. Among authors: van tellingen o. Trends Mol Med. 2018 Sep;24(9):763-780. doi: 10.1016/j.molmed.2018.07.003. Epub 2018 Jul 30. Trends Mol Med. 2018. PMID: 30072121 Review.
EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.
Puppe J, Opdam M, Schouten PC, Jóźwiak K, Lips E, Severson T, van de Ven M, Brambillasca C, Bouwman P, van Tellingen O, Bernards R, Wesseling J, Eichler C, Thangarajah F, Malter W, Pandey GK, Ozretić L, Caldas C, van Lohuizen M, Hauptmann M, Rhiem K, Hahnen E, Reinhardt HC, Büttner R, Mallmann P, Schömig-Markiefka B, Schmutzler R, Linn S, Jonkers J. Puppe J, et al. Among authors: van de ven m, van tellingen o, van lohuizen m. Clin Cancer Res. 2019 Jul 15;25(14):4351-4362. doi: 10.1158/1078-0432.CCR-18-4024. Epub 2019 Apr 29. Clin Cancer Res. 2019. PMID: 31036541
SLC1A3 contributes to L-asparaginase resistance in solid tumors.
Sun J, Nagel R, Zaal EA, Ugalde AP, Han R, Proost N, Song JY, Pataskar A, Burylo A, Fu H, Poelarends GJ, van de Ven M, van Tellingen O, Berkers CR, Agami R. Sun J, et al. Among authors: van de ven m, van tellingen o. EMBO J. 2019 Oct 4;38(21):e102147. doi: 10.15252/embj.2019102147. Epub 2019 Sep 16. EMBO J. 2019. PMID: 31523835 Free PMC article.
Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours.
Fernandes Neto JM, Nadal E, Bosdriesz E, Ooft SN, Farre L, McLean C, Klarenbeek S, Jurgens A, Hagen H, Wang L, Felip E, Martinez-Marti A, Vidal A, Voest E, Wessels LFA, van Tellingen O, Villanueva A, Bernards R. Fernandes Neto JM, et al. Among authors: van tellingen o. Nat Commun. 2020 Jun 22;11(1):3157. doi: 10.1038/s41467-020-16952-9. Nat Commun. 2020. PMID: 32572029 Free PMC article.
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.
Pogacar Z, Johnson JL, Krenning L, De Conti G, Jochems F, Lieftink C, Velds A, Wardak L, Groot K, Schepers A, Wang L, Song JY, van de Ven M, van Tellingen O, Medema RH, Beijersbergen RL, Bernards R, Leite de Oliveira R. Pogacar Z, et al. Among authors: van de ven m, van tellingen o. PLoS One. 2022 Sep 6;17(9):e0273182. doi: 10.1371/journal.pone.0273182. eCollection 2022. PLoS One. 2022. PMID: 36067171 Free PMC article.
Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.
Uceda-Castro R, Margarido AS, Cornet L, Vegna S, Hahn K, Song JY, Putavet DA, van Geldorp M, Çitirikkaya CH, de Keizer PLJ, Ter Beek LC, Borst GR, Akkari L, van Tellingen O, Broekman MLD, Vennin C, van Rheenen J. Uceda-Castro R, et al. Among authors: van tellingen o, van geldorp m, van rheenen j. Cell Rep Med. 2022 Nov 15;3(11):100821. doi: 10.1016/j.xcrm.2022.100821. Cell Rep Med. 2022. PMID: 36384097 Free PMC article.
Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.
Mulero-Sánchez A, Ramirez CFA, du Chatinier A, Wang H, Koomen SJI, Song JY, de Groot MHP, Lieftink C, Bosma A, Burylo A, van Tellingen O, Beijersbergen RL, Wang C, Akkari L, Bernards R, Mainardi S. Mulero-Sánchez A, et al. Among authors: van tellingen o. Mol Oncol. 2023 Jun;17(6):964-980. doi: 10.1002/1878-0261.13377. Epub 2023 Feb 9. Mol Oncol. 2023. PMID: 36650715 Free PMC article.
222 results