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IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.
Schmacke NA, O'Duill F, Gaidt MM, Szymanska I, Kamper JM, Schmid-Burgk JL, Mädler SC, Mackens-Kiani T, Kozaki T, Chauhan D, Nagl D, Stafford CA, Harz H, Fröhlich AL, Pinci F, Ginhoux F, Beckmann R, Mann M, Leonhardt H, Hornung V. Schmacke NA, et al. Among authors: beckmann r. Immunity. 2022 Dec 13;55(12):2271-2284.e7. doi: 10.1016/j.immuni.2022.10.021. Epub 2022 Nov 15. Immunity. 2022. PMID: 36384135 Free PMC article.
A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog F, Fromont-Racine M, Becker T, Beckmann R. Kratzat H, et al. Among authors: beckmann r. EMBO J. 2021 Jan 4;40(1):e105179. doi: 10.15252/embj.2020105179. Epub 2020 Dec 8. EMBO J. 2021. PMID: 33289941 Free PMC article.
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T, Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T, Cheng J, Straub JH, Stürzel CM, Fröhlich T, Berninghausen O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R. Thoms M, et al. Among authors: beckmann r. Science. 2020 Sep 4;369(6508):1249-1255. doi: 10.1126/science.abc8665. Epub 2020 Jul 17. Science. 2020. PMID: 32680882 Free PMC article.
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage.
Park E, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR. Park E, et al. Among authors: beckmann r. bioRxiv [Preprint]. 2023 May 6:2023.05.05.539626. doi: 10.1101/2023.05.05.539626. bioRxiv. 2023. PMID: 37205477 Free PMC article. Updated. Preprint.
B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage.
Park EN, Mackens-Kiani T, Berhane R, Esser H, Erdenebat C, Burroughs AM, Berninghausen O, Aravind L, Beckmann R, Green R, Buskirk AR. Park EN, et al. Among authors: beckmann r. EMBO J. 2024 Feb;43(4):484-506. doi: 10.1038/s44318-023-00010-3. Epub 2023 Dec 14. EMBO J. 2024. PMID: 38177497 Free PMC article.
454 results