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IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.
Schmacke NA, O'Duill F, Gaidt MM, Szymanska I, Kamper JM, Schmid-Burgk JL, Mädler SC, Mackens-Kiani T, Kozaki T, Chauhan D, Nagl D, Stafford CA, Harz H, Fröhlich AL, Pinci F, Ginhoux F, Beckmann R, Mann M, Leonhardt H, Hornung V. Schmacke NA, et al. Among authors: leonhardt h. Immunity. 2022 Dec 13;55(12):2271-2284.e7. doi: 10.1016/j.immuni.2022.10.021. Epub 2022 Nov 15. Immunity. 2022. PMID: 36384135 Free PMC article.
Universal Super-Resolution Multiplexing by DNA Exchange.
Schueder F, Strauss MT, Hoerl D, Schnitzbauer J, Schlichthaerle T, Strauss S, Yin P, Harz H, Leonhardt H, Jungmann R. Schueder F, et al. Among authors: leonhardt h. Angew Chem Int Ed Engl. 2017 Mar 27;56(14):4052-4055. doi: 10.1002/anie.201611729. Epub 2017 Mar 3. Angew Chem Int Ed Engl. 2017. PMID: 28256790 Free PMC article.
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Andreeva L, Hiller B, Kostrewa D, Lässig C, de Oliveira Mann CC, Jan Drexler D, Maiser A, Gaidt M, Leonhardt H, Hornung V, Hopfner KP. Andreeva L, et al. Among authors: leonhardt h. Nature. 2017 Sep 21;549(7672):394-398. doi: 10.1038/nature23890. Epub 2017 Sep 13. Nature. 2017. PMID: 28902841
In vitro and in vivo delivery of siRNA via VIPER polymer system to lung cells.
Feldmann DP, Cheng Y, Kandil R, Xie Y, Mohammadi M, Harz H, Sharma A, Peeler DJ, Moszczynska A, Leonhardt H, Pun SH, Merkel OM. Feldmann DP, et al. Among authors: leonhardt h. J Control Release. 2018 Apr 28;276:50-58. doi: 10.1016/j.jconrel.2018.02.017. Epub 2018 Feb 20. J Control Release. 2018. PMID: 29474962 Free PMC article.
Linker Molecules Convert Commercial Fluorophores into Tailored Functional Probes during Biolabelling.
Zhang L, Isselstein M, Köhler J, Eleftheriadis N, Huisjes NM, Guirao-Ortiz M, Narducci A, Smit JH, Stoffels J, Harz H, Leonhardt H, Herrmann A, Cordes T. Zhang L, et al. Among authors: leonhardt h. Angew Chem Int Ed Engl. 2022 May 2;61(19):e202112959. doi: 10.1002/anie.202112959. Epub 2022 Feb 26. Angew Chem Int Ed Engl. 2022. PMID: 35146855 Free PMC article.
Differences in nanoscale organization of regulatory active and inactive human chromatin.
Brandstetter K, Zülske T, Ragoczy T, Hörl D, Guirao-Ortiz M, Steinek C, Barnes T, Stumberger G, Schwach J, Haugen E, Rynes E, Korber P, Stamatoyannopoulos JA, Leonhardt H, Wedemann G, Harz H. Brandstetter K, et al. Among authors: leonhardt h. Biophys J. 2022 Mar 15;121(6):977-990. doi: 10.1016/j.bpj.2022.02.009. Epub 2022 Feb 10. Biophys J. 2022. PMID: 35150617 Free PMC article.
523 results