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IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.
Schmacke NA, O'Duill F, Gaidt MM, Szymanska I, Kamper JM, Schmid-Burgk JL, Mädler SC, Mackens-Kiani T, Kozaki T, Chauhan D, Nagl D, Stafford CA, Harz H, Fröhlich AL, Pinci F, Ginhoux F, Beckmann R, Mann M, Leonhardt H, Hornung V. Schmacke NA, et al. Among authors: madler sc. Immunity. 2022 Dec 13;55(12):2271-2284.e7. doi: 10.1016/j.immuni.2022.10.021. Epub 2022 Nov 15. Immunity. 2022. PMID: 36384135 Free PMC article.
Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome.
Rosenberger FA, Thielert M, Strauss MT, Schweizer L, Ammar C, Mädler SC, Metousis A, Skowronek P, Wahle M, Madden K, Gote-Schniering J, Semenova A, Schiller HB, Rodriguez E, Nordmann TM, Mund A, Mann M. Rosenberger FA, et al. Among authors: madler sc. Nat Methods. 2023 Oct;20(10):1530-1536. doi: 10.1038/s41592-023-02007-6. Epub 2023 Oct 2. Nat Methods. 2023. PMID: 37783884 Free PMC article.
Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research.
Mädler SC, Julien-Laferriere A, Wyss L, Phan M, Sonrel A, Kang ASW, Ulrich E, Schmucki R, Zhang JD, Ebeling M, Badi L, Kam-Thong T, Schwalie PC, Hatje K. Mädler SC, et al. NAR Genom Bioinform. 2021 Nov 8;3(4):lqab102. doi: 10.1093/nargab/lqab102. eCollection 2021 Dec. NAR Genom Bioinform. 2021. PMID: 34761219 Free PMC article.