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Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity.
J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):198-213. doi: 10.1002/jcsm.13121. Epub 2022 Nov 17.
J Cachexia Sarcopenia Muscle. 2023.
PMID: 36398408
Free PMC article.
Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice.
Ang SJ, Crombie EM, Dong H, Tan KT, Hernando A, Yu D, Adamson S, Kim S, Withers DJ, Huang H, Tsai SY.
Ang SJ, et al. Among authors: crombie em.
Nat Commun. 2022 Dec 17;13(1):7792. doi: 10.1038/s41467-022-35547-0.
Nat Commun. 2022.
PMID: 36526657
Free PMC article.
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Paraspinal myopathy-induced intervertebral disc degeneration and thoracolumbar kyphosis in TSC1mKO mice model-a preliminary study.
Hey HWD, Lam WMR, Chan CX, Zhuo WH, Crombie EM, Tan TC, Chen WC, Cool S, Tsai SY.
Hey HWD, et al. Among authors: crombie em.
Spine J. 2022 Mar;22(3):483-494. doi: 10.1016/j.spinee.2021.09.003. Epub 2021 Oct 13.
Spine J. 2022.
PMID: 34653636
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Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.
Crombie EM, Korecki AJ, Cleverley K, Adair BA, Cunningham TJ, Lee WC, Lengyell TC, Maduro C, Mo V, Slade LM, Zouhair I, Fisher EMC, Simpson EM.
Crombie EM, et al.
Dis Model Mech. 2024 May 28:dmm.050741. doi: 10.1242/dmm.050741. Online ahead of print.
Dis Model Mech. 2024.
PMID: 38804708
Free article.
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