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Page 1
Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice.
Galsgaard KD, Elmelund E, Johansen CD, Bomholt AB, Kizilkaya HS, Ceutz F, Hunt JE, Kissow H, Winther-Sørensen M, Sørensen CM, Kruse T, Lau JF, Rosenkilde MM, Ørskov C, Christoffersen C, Holst JJ, Wewer Albrechtsen NJ. Galsgaard KD, et al. Among authors: orskov c. Mol Metab. 2022 Dec;66:101639. doi: 10.1016/j.molmet.2022.101639. Epub 2022 Nov 15. Mol Metab. 2022. PMID: 36400402 Free PMC article.
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis.
Winther-Sørensen M, Galsgaard KD, Santos A, Trammell SAJ, Sulek K, Kuhre RE, Pedersen J, Andersen DB, Hassing AS, Dall M, Treebak JT, Gillum MP, Torekov SS, Windeløv JA, Hunt JE, Kjeldsen SAS, Jepsen SL, Vasilopoulou CG, Knop FK, Ørskov C, Werge MP, Bisgaard HC, Eriksen PL, Vilstrup H, Gluud LL, Holst JJ, Wewer Albrechtsen NJ. Winther-Sørensen M, et al. Among authors: orskov c. Mol Metab. 2020 Dec;42:101080. doi: 10.1016/j.molmet.2020.101080. Epub 2020 Sep 13. Mol Metab. 2020. PMID: 32937194 Free PMC article.
Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis.
Galsgaard KD, Winther-Sørensen M, Ørskov C, Kissow H, Poulsen SS, Vilstrup H, Prehn C, Adamski J, Jepsen SL, Hartmann B, Hunt J, Charron MJ, Pedersen J, Wewer Albrechtsen NJ, Holst JJ. Galsgaard KD, et al. Among authors: orskov c. Am J Physiol Endocrinol Metab. 2018 Jan 1;314(1):E93-E103. doi: 10.1152/ajpendo.00198.2017. Epub 2017 Oct 3. Am J Physiol Endocrinol Metab. 2018. PMID: 28978545 Free PMC article.
Investigating Intestinal Glucagon After Roux-en-Y Gastric Bypass Surgery.
Jorsal T, Wewer Albrechtsen NJ, Christensen MM, Mortensen B, Wandall E, Langholz E, Friis S, Worm D, Ørskov C, Støving RK, Andries A, Juhl CB, Sørensen F, Forman JL, Falkenhahn M, Musholt PB, Theis S, Larsen PJ, Holst JJ, Vrang N, Jelsing J, Vilsbøll T, Knop FK. Jorsal T, et al. Among authors: orskov c. J Clin Endocrinol Metab. 2019 Dec 1;104(12):6403-6416. doi: 10.1210/jc.2019-00062. J Clin Endocrinol Metab. 2019. PMID: 31276156
Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in mice.
Jepsen SL, Grunddal KV, Wewer Albrechtsen NJ, Engelstoft MS, Gabe MBN, Jensen EP, Ørskov C, Poulsen SS, Rosenkilde MM, Pedersen J, Gribble FM, Reimann F, Deacon CF, Schwartz TW, Christ AD, Martin RE, Holst JJ. Jepsen SL, et al. Among authors: orskov c. Am J Physiol Endocrinol Metab. 2019 Dec 1;317(6):E1081-E1093. doi: 10.1152/ajpendo.00239.2019. Epub 2019 Sep 10. Am J Physiol Endocrinol Metab. 2019. PMID: 31503512 Free PMC article.
Glucagon receptor signaling is not required for N-carbamoyl glutamate- and l-citrulline-induced ureagenesis in mice.
Galsgaard KD, Pedersen J, Kjeldsen SAS, Winther-Sørensen M, Stojanovska E, Vilstrup H, Ørskov C, Wewer Albrechtsen NJ, Holst JJ. Galsgaard KD, et al. Among authors: orskov c. Am J Physiol Gastrointest Liver Physiol. 2020 May 1;318(5):G912-G927. doi: 10.1152/ajpgi.00294.2019. Epub 2020 Mar 16. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 32174131 Free article.
Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression.
Bomholt AB, Johansen CD, Christensen JB, Kjeldsen SAS, Galsgaard KD, Winther-Sørensen M, Serizawa R, Hornum M, Porrini E, Pedersen J, Ørskov C, Gluud LL, Sørensen CM, Holst JJ, Albrechtsen R, Wewer Albrechtsen NJ. Bomholt AB, et al. Among authors: orskov c. Commun Biol. 2022 Nov 22;5(1):1278. doi: 10.1038/s42003-022-04242-7. Commun Biol. 2022. PMID: 36418521 Free PMC article.
122 results