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Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice.
Galsgaard KD, Elmelund E, Johansen CD, Bomholt AB, Kizilkaya HS, Ceutz F, Hunt JE, Kissow H, Winther-Sørensen M, Sørensen CM, Kruse T, Lau JF, Rosenkilde MM, Ørskov C, Christoffersen C, Holst JJ, Wewer Albrechtsen NJ. Galsgaard KD, et al. Among authors: elmelund e. Mol Metab. 2022 Dec;66:101639. doi: 10.1016/j.molmet.2022.101639. Epub 2022 Nov 15. Mol Metab. 2022. PMID: 36400402 Free PMC article.
Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells.
Elmelund E, Galsgaard KD, Johansen CD, Trammell SAJ, Bomholt AB, Winther-Sørensen M, Hunt JE, Sørensen CM, Kruse T, Lau JF, Grevengoed TJ, Holst JJ, Wewer Albrechtsen NJ. Elmelund E, et al. iScience. 2022 Oct 6;25(11):105296. doi: 10.1016/j.isci.2022.105296. eCollection 2022 Nov 18. iScience. 2022. PMID: 36325048 Free PMC article.
Arginine-induced glucagon secretion and glucagon-induced enhancement of amino acid catabolism are not influenced by ambient glucose levels in mice.
Maruszczak K, Rasmussen C, Ceutz FR, Ørgaard A, Elmelund E, Richter MM, Holst JJ, Winther-Sørensen M, Wewer Albrechtsen NJ. Maruszczak K, et al. Among authors: elmelund e. Am J Physiol Endocrinol Metab. 2022 Sep 1;323(3):E207-E214. doi: 10.1152/ajpendo.00122.2022. Epub 2022 Jul 13. Am J Physiol Endocrinol Metab. 2022. PMID: 35830690 Free article.
The Liver-α-Cell Axis in Health and in Disease.
Richter MM, Galsgaard KD, Elmelund E, Knop FK, Suppli MP, Holst JJ, Winther-Sørensen M, Kjeldsen SAS, Wewer Albrechtsen NJ. Richter MM, et al. Among authors: elmelund e. Diabetes. 2022 Sep 1;71(9):1852-1861. doi: 10.2337/dbi22-0004. Diabetes. 2022. PMID: 35657688 Free PMC article. Review.