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Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice.
Galsgaard KD, Elmelund E, Johansen CD, Bomholt AB, Kizilkaya HS, Ceutz F, Hunt JE, Kissow H, Winther-Sørensen M, Sørensen CM, Kruse T, Lau JF, Rosenkilde MM, Ørskov C, Christoffersen C, Holst JJ, Wewer Albrechtsen NJ. Galsgaard KD, et al. Among authors: sorensen cm. Mol Metab. 2022 Dec;66:101639. doi: 10.1016/j.molmet.2022.101639. Epub 2022 Nov 15. Mol Metab. 2022. PMID: 36400402 Free PMC article.
Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow.
Jensen EP, Poulsen SS, Kissow H, Holstein-Rathlou NH, Deacon CF, Jensen BL, Holst JJ, Sorensen CM. Jensen EP, et al. Among authors: sorensen cm. Am J Physiol Renal Physiol. 2015 Apr 15;308(8):F867-77. doi: 10.1152/ajprenal.00527.2014. Epub 2015 Feb 4. Am J Physiol Renal Physiol. 2015. PMID: 25656368 Free article.
Glucagon-like peptide-1 does not have acute effects on central or renal hemodynamics in patients with type 2 diabetes without nephropathy.
Asmar A, Simonsen L, Asmar M, Madsbad S, Holst JJ, Frandsen E, Moro C, Sorensen CM, Jonassen T, Bülow J. Asmar A, et al. Among authors: sorensen cm. Am J Physiol Endocrinol Metab. 2016 May 1;310(9):E744-53. doi: 10.1152/ajpendo.00518.2015. Epub 2016 Mar 8. Am J Physiol Endocrinol Metab. 2016. PMID: 26956188 Free article.
238 results