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Glycobiology of rheumatic diseases.
Kissel T, Toes REM, Huizinga TWJ, Wuhrer M. Kissel T, et al. Among authors: wuhrer m. Nat Rev Rheumatol. 2023 Jan;19(1):28-43. doi: 10.1038/s41584-022-00867-4. Epub 2022 Nov 23. Nat Rev Rheumatol. 2023. PMID: 36418483 Free PMC article. Review.
Fc-glycosylation of IgG1 is modulated by B-cell stimuli.
Wang J, Balog CI, Stavenhagen K, Koeleman CA, Scherer HU, Selman MH, Deelder AM, Huizinga TW, Toes RE, Wuhrer M. Wang J, et al. Among authors: wuhrer m. Mol Cell Proteomics. 2011 May;10(5):M110.004655. doi: 10.1074/mcp.M110.004655. Epub 2011 Mar 3. Mol Cell Proteomics. 2011. PMID: 21372248 Free PMC article.
Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.
Rombouts Y, Willemze A, van Beers JJ, Shi J, Kerkman PF, van Toorn L, Janssen GM, Zaldumbide A, Hoeben RC, Pruijn GJ, Deelder AM, Wolbink G, Rispens T, van Veelen PA, Huizinga TW, Wuhrer M, Trouw LA, Scherer HU, Toes RE. Rombouts Y, et al. Among authors: wuhrer m. Ann Rheum Dis. 2016 Mar;75(3):578-85. doi: 10.1136/annrheumdis-2014-206598. Epub 2015 Jan 13. Ann Rheum Dis. 2016. PMID: 25587188
Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.
Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G. Pfeifle R, et al. Among authors: wuhrer m. Nat Immunol. 2017 Jan;18(1):104-113. doi: 10.1038/ni.3579. Epub 2016 Nov 7. Nat Immunol. 2017. PMID: 27820809 Free PMC article.
Adaptive antibody diversification through N-linked glycosylation of the immunoglobulin variable region.
van de Bovenkamp FS, Derksen NIL, Ooijevaar-de Heer P, van Schie KA, Kruithof S, Berkowska MA, van der Schoot CE, IJspeert H, van der Burg M, Gils A, Hafkenscheid L, Toes REM, Rombouts Y, Plomp R, Wuhrer M, van Ham SM, Vidarsson G, Rispens T. van de Bovenkamp FS, et al. Among authors: wuhrer m. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1901-1906. doi: 10.1073/pnas.1711720115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432186 Free PMC article.
Low amounts of bisecting glycans characterize cerebrospinal fluid-borne IgG.
Knopf J, Magorivska I, Maler JM, Spitzer P, Bilyy R, Biermann MHC, Hychka K, Bondt A, Wuhrer M, Toes REM, Schett G, Herrmann M, Muñoz LE. Knopf J, et al. Among authors: wuhrer m. J Neuroimmunol. 2018 Jul 15;320:19-24. doi: 10.1016/j.jneuroim.2018.04.010. Epub 2018 Apr 16. J Neuroimmunol. 2018. PMID: 29759137
447 results